Modifiable Lifestyle Risk Factors and Incident Diabetes in African Americans.
Modifiable Lifestyle Risk Factors and Incident Diabetes in African Americans.
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DOI:
10.1016/j.amepre.2017.06.018
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发表时间:
2017-11
影响因子:
5.5
通讯作者:
Golden SH
中科院分区:
文献类型:
--
作者:
Joseph JJ;Echouffo-Tcheugui JB;Talegawkar SA;Effoe VS;Okhomina V;Carnethon MR;Hsueh WA;Golden SH
The associations of modifiable lifestyle risk factors with incident diabetes are not well investigated in African Americans (AAs). This study investigated the association of modifiable lifestyle risk factors (exercise, diet, smoking, TV watching, and sleep disordered breathing burden) with incident diabetes among AAs. Modifiable lifestyle risk factors were characterized among 3,252 AAs in the Jackson Heart Study free of diabetes at baseline (2000–2004) using baseline questionnaires and combined into risk factor categories: poor (0–3 points), average (4–7 points), and optimal (8–11 points). Incidence rate ratios (IRR) for diabetes (fasting glucose ≥126 mg/dL, physician diagnosis, use of diabetes drugs, or glycosylated hemoglobin A1c (HbA1c) ≥6.5%) were estimated using Poisson regression modeling adjusting for age, sex, education, occupation, systolic blood pressure, and BMI. Outcomes were collected 2005–2012 and data analyzed in 2016. Over 7.6 years there were 560 incident diabetes cases (mean age=53.3 years, 64% female). An average or optimal compared to a poor risk factor categorization was associated with a 21% (IRR=0.79, 95% CI=0.62, 0.99) and 31% (IRR=0.69, 95% CI=0.48, 1.01) lower risk of diabetes. Among BMI <30 kg/m2 participants, IRRs for average or optimal compared to poor categorization were 0.60 (95% CI=0.40, 0.91) and 0.53 (95% CI=0.29, 0.97), versus 0.90 (95% CI=0.67, 1.21) and 0.83 (95% CI=0.51, 1.34) among participants with BMI ≥30 kg/m2. A combination of modifiable lifestyle factors are associated with a lower risk of diabetes among AAs, particularly among those without obesity.
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影响因子:
158.5
作者:
Knowler, WC;Barrett-Connor, E;Nathan, DM
通讯作者:
Nathan, DM
影响因子:
16.2
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16.2
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158.5
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Hu, FB;Manson, JE;Willett, WC
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Willett, WC
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8.2
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通讯作者:
Golden SH