Negative Vaccine Attitudes and Intentions to Vaccinate Against Covid-19 in Relation to Smoking Status: A Population Survey of UK Adults.

Negative Vaccine Attitudes and Intentions to Vaccinate Against Covid-19 in Relation to Smoking Status: A Population Survey of UK Adults.
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DOI:
10.1093/ntr/ntab039
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发表时间:
2021-08-18
期刊:
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
影响因子:
--
通讯作者:
Fancourt D
Fancourt D
中科院分区:
其他
文献类型:
--
作者:
Jackson SE;Paul E;Brown J;Steptoe A;Fancourt D

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我们通过对英国成年人的大样本吸烟情况,考察了他们对疫苗总体上的负面态度以及接种新冠肺炎疫苗意图的差异。数据来自于2020年9月至10月参与新冠肺炎社会研究的29 148名成年人。线性回归分析考察了吸烟状况(现在/以前/从不吸烟)与四种普遍的负面疫苗态度之间的关系:不信任疫苗益处,担心不可预见的影响,担心商业牟取暴利,以及偏爱自然免疫。多项Logistic回归分析了吸烟状况与新冠肺炎接种的不确定性和不愿接种疫苗之间的关系。协变量包括社会人口学特征和诊断的健康状况。与从不吸烟者和曾经吸烟者相比,现在吸烟者对疫苗的益处更不信任,更担心不可预见的未来影响,更担心商业牟取暴利,更倾向于自然免疫(Badjs 0.16-0.36,p<.001)。现在吸烟者更有可能不确定(27.6%比22.7%从不吸烟者,RRadj1.43[95%可信区间=1.31-1.56];比既往吸烟者19.3%RRadj1.55[1.41-1.73])或不愿意(21.5%比11.6%不吸烟者RRadj2.12[1.91-2.34];比14.7%曾经吸烟者RRadj1.53[1.37-1.71])接种新冠肺炎疫苗。与从不吸烟者和曾经吸烟者相比,当前吸烟者总体上对疫苗持更负面的态度,更有可能犹豫不决或不愿接种新冠肺炎疫苗。由于属于社会集群化和弱势社会经济群体的吸烟者数量不成比例地高,这一群体的疫苗接种量较低也可能加剧健康不平等。这些结果表明,在没有干预的情况下,吸烟者比不吸烟者在新冠肺炎疫苗提供时接受的可能性更小。可能需要采取有针对性的政策行动,以确保新冠肺炎疫苗接种计划的低接种率不会加剧吸烟者和不吸烟者之间的健康不平等。
We examined differences in negative attitudes toward vaccines in general, and intentions to vaccinate against Covid-19 specifically, by smoking status in a large sample of adults in the UK. Data were from 29 148 adults participating in the Covid-19 Social Study in September–October 2020. Linear regression analyses examined associations between smoking status (current/former/never) and four types of general negative vaccine attitudes: mistrust of vaccine benefit, worries about unforeseen effects, concerns about commercial profiteering, and preference for natural immunity. Multinomial logistic regression examined associations between smoking status and uncertainty and unwillingness to be vaccinated for Covid-19. Covariates included sociodemographic characteristics and diagnosed health conditions. Relative to never and former smokers, current smokers reported significantly greater mistrust of vaccine benefit, were more worried about unforeseen future effects, had greater concerns about commercial profiteering, and had a stronger preference for natural immunity (Badjs 0.16–0.36, p < .001). Current smokers were more likely to be uncertain (27.6% vs. 22.7% of never smokers, RRadj 1.43 [95% confidence interval = 1.31–1.56]; vs. 19.3% of former smokers, RRadj 1.55 [1.41–1.73]) or unwilling (21.5% vs. 11.6% of never smokers, RRadj 2.12 [1.91–2.34]; vs. 14.7% of former smokers, RRadj 1.53 [1.37–1.71]) to receive a Covid-19 vaccine. Current smokers hold more negative attitudes toward vaccines in general, and are more likely to be undecided or unwilling to vaccinate against Covid-19, compared with never and former smokers. With a disproportionately high number of smokers belonging to socially clustered and disadvantaged socioeconomic groups, lower vaccine uptake in this group could also exacerbate health inequalities. These results suggest that without intervention, smokers will be less likely than nonsmokers to take up the offer of a Covid-19 vaccine when offered. Targeted policy action may be required to ensure that low uptake of Covid-19 vaccination programs does not compound health inequalities between smokers and nonsmokers.
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