Assessing ethanol's actions in the suprachiasmatic circadian clock using in vivo and in vitro approaches.

Assessing ethanol's actions in the suprachiasmatic circadian clock using in vivo and in vitro approaches.
复制标题

使用体内和体外方法评估乙醇在视交叉上生物钟中的作用。

DOI:
10.1016/j.alcohol.2014.07.016
复制
发表时间:
2015
期刊:
Alcohol (Fayetteville, N.Y.)
影响因子:
--
通讯作者:
Glass,JDavid
Glass,JDavid
中科院分区:
--
文献类型:
--
作者:
Prosser,RebeccaA;Glass,JDavid

文献摘要

参考文献

被引文献

相似文献

过去十年的研究表明,昼夜节律系统与酒精影响行为和生理的过程之间存在实质性的相互作用。在这里,我们总结了我们在这个交叉点上共同努力的结果。通过体内和体外方法的结合,我们已经证明了乙醇对哺乳动物昼夜节律系统的许多方面都有影响,无论是急性的还是慢性的。相反,我们已经证明了昼夜节律对乙醇消耗的影响。重要的是,我们正开始深入研究与这些效应相关的细胞机制。我们也开始形成许多这些动作的神经解剖学基础的图像。最后,我们通过为我们未来的努力提出新的调查途径,将我们目前的发现纳入观点。
Research over the past decade has demonstrated substantial interactions between the circadian system and the processes through which alcohol affects behavior and physiology. Here we summarize the results of our collaborative efforts focused on this intersection. Using a combination ofin vivoandin vitroapproaches, we have shown that ethanol affects many aspects of the mammalian circadian system, both acutely as well as after chronic administration. Conversely, we have shown circadian influences on ethanol consumption. Importantly, we are beginning to delve into the cellular mechanisms associated with these effects. We are also starting to form a picture of the neuroanatomical bases for many of these actions. Finally, we put our current findings into perspective by suggesting new avenues of inquiry for our future efforts.
DOI: 10.1177/0748730409346657
发表时间: 2009-12-01
影响因子: 3.5
作者:
Webb, Ian C.;Baltazar, Ricardo M.;Lehman, Michael N.
通讯作者: Lehman, Michael N.
DOI: 10.1186/1740-3391-8-1
发表时间: 2010-01-21
影响因子: --
作者:
Sjöholm LK;Kovanen L;Saarikoski ST;Schalling M;Lavebratt C;Partonen T
通讯作者: Partonen T
昼夜节律对光反应的行为抑制
DOI: --
发表时间: 1992
影响因子: 3.5
作者:
M. Ralph;Nicholas Mrosovsky
通讯作者: Nicholas Mrosovsky
血清素激动剂在体外使视交叉上核的生物钟发生相移
DOI: 10.1016/0006-8993(90)90153-3
发表时间: 1990
期刊: Brain Research
影响因子: 2.9
作者:
R. Prosser;Joseph D. Miller;H. Heller
通讯作者: H. Heller
通过体内微透析评估西伯利亚仓鼠视交叉上区域 5-羟基吲哚-乙酸输出的昼夜变化:夜间激活血清素释放的证据。
DOI: 10.1159/000126277
发表时间: 1992
期刊: Neuroendocrinology
影响因子: 4.1
作者:
J. Glass;W. Randolph;S. Ferreira;M. Rea;U. E. Hauser;J. Blank;M. D. de Vries
通讯作者: M. D. de Vries