Pulse wave propagation in a model human arterial network: Assessment of 1-D visco-elastic simulations against in vitro measurements.
Pulse wave propagation in a model human arterial network: Assessment of 1-D visco-elastic simulations against in vitro measurements.
复制标题
人体动脉网络模型中的脉搏波传播：根据体外测量评估一维粘弹性模拟。
DOI：
10.1016/j.jbiomech.2011.05.041
复制
发表时间：
2011-08-11
影响因子：
2.4
通讯作者：
Peiro, Joaquim
中科院分区：
文献类型：
--
作者：
Alastruey, Jordi;Khir, Ashraf W.;Matthys, Koen S.;Segers, Patrick;Sherwin, Spencer J.;Verdonck, Pascal R.;Parker, Kim H.;Peiro, Joaquim
关键词：
对Voigt型粘弹性动脉中压力和流量波传播的非线性一维(1-D)方程的准确性进行了测试，并与人体体循环中37条最大的管道动脉1：1复制品的测量结果进行了对比。数值算法所需的参数是在体外装置中直接测量的，不涉及数据拟合。数值模型中的壁粘弹性减少了使用纯弹性管律获得的欠阻尼高频振荡，特别是在外周血管中，这在本论文中曾报道过[Matthys等人，2007年。脉搏波在模型人体动脉网络中的传播：1-D数值模拟对照体外测量的评估。J.Biomech。40,3476-3486]。与纯弹性模型相比，粘弹性显著降低了体外模型中70个测点的数值波形和实验波形的平均相对均方根误差：压力从3.0%降至2.5%，流量从15.7%降至10.8%。在频域内，从5次谐波到20次谐波的数值幅值和实验幅值的平均相对误差分别从0.7%和7.0%下降到0.5%和3.3%。这些结果为使用一维简化模型以合理的计算成本准确模拟临床相关问题提供了额外的支持。►我们测试了大动脉中血液流动的一维非线性方程的准确性。►我们将硅胶树中的波浪测量结果与数值预测进行了比较。►一维建模能够捕捉到脉搏波的主要特征。墙体粘弹性的►模拟显著减小了相对误差。分叉处的►能量损失对脉冲波形有二次影响。
The accuracy of the nonlinear one-dimensional (1-D) equations of pressure and flow wave propagation in Voigt-type visco-elastic arteries was tested against measurements in a well-defined experimental 1:1 replica of the 37 largest conduit arteries in the human systemic circulation. The parameters required by the numerical algorithm were directly measured in the in vitro setup and no data fitting was involved. The inclusion of wall visco-elasticity in the numerical model reduced the underdamped high-frequency oscillations obtained using a purely elastic tube law, especially in peripheral vessels, which was previously reported in this paper [Matthys et al., 2007. Pulse wave propagation in a model human arterial network: Assessment of 1-D numerical simulations against in vitro measurements. J. Biomech. 40, 3476–3486]. In comparison to the purely elastic model, visco-elasticity significantly reduced the average relative root-mean-square errors between numerical and experimental waveforms over the 70 locations measured in the in vitro model: from 3.0% to 2.5% for pressure and from 15.7% to 10.8% for the flow rate. In the frequency domain, average relative errors between numerical and experimental amplitudes from the 5th to the 20th harmonic decreased from 0.7% to 0.5% for pressure and from 7.0% to 3.3% for the flow rate. These results provide additional support for the use of 1-D reduced modelling to accurately simulate clinically relevant problems at a reasonable computational cost. ► We test the accuracy of the nonlinear 1-D equations of blood flow in large arteries. ► We compare wave measurements in a silicone tree with numerical predictions. ► 1-D modelling is able to capture the main features of pulse waveforms. ► Simulation of wall visco-elasticity significantly decreases relative errors. ► Energy losses at bifurcations have a secondary effect on pulse waveforms.
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影响因子：
2.4
作者：
STERGIOPULOS, N;YOUNG, DF;ROGGE, TR
通讯作者：
ROGGE, TR
影响因子：
2.4
作者：
Segers, P;Verdonck, P
通讯作者：
Verdonck, P
影响因子：
2.9
作者：
Cockburn, B;Shu, CW
通讯作者：
Shu, CW
DOI：
10.1152/ajpheart.00037.2009
发表时间：
2009-07-01
影响因子：
4.8
作者：
Reymond, Philippe;Merenda, Fabrice;Stergiopulos, Nikos
通讯作者：
Stergiopulos, Nikos
影响因子：
4.6
作者：
Valdez-Jasso, Daniela;Haider, Mansoor A.;Olufsen, Mette S.
通讯作者：
Olufsen, Mette S.