Impact of visceral adiposity measured by abdominal computed tomography on pulmonary function.
Impact of visceral adiposity measured by abdominal computed tomography on pulmonary function.
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DOI：
10.3346/jkms.2011.26.6.771
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发表时间：
2011-06
影响因子：
4.5
通讯作者：
Yim JJ
中科院分区：
文献类型：
--
作者：
Park YS;Kwon HT;Hwang SS;Choi SH;Cho YM;Lee J;Yim JJ
虽然腹部脂肪和肺功能之间的反比关系已经提出，直接测量腹部脂肪组织很少尝试。我们的目的是通过腹部计算机断层扫描（CT）直接测量腹部脂肪组织来确定腹部肥胖对肺功能的影响。在这项横断面研究中，我们纳入了年龄在18岁至85岁之间的从不吸烟者，他们在2005年11月1日至2009年10月31日期间接受了肺功能测定和腹部脂肪组织分析以及CT扫描，作为全面健康检查的一部分。在总共3 469名参与者中，890名（25.7%）是男性。男性和女性的平均体重指数和腰围分别为24.6 kg/m2和87.8 cm以及23.0 kg/m2和83.0 cm。尽管雄性（269.1 cm 2）的腹部总脂肪组织（达特）与雌性（273.6 cm 2）相似，但内脏脂肪组织（VAT）/皮下脂肪组织（SAT）的比值不同;雄性为0.99，雌性为0.50。在男性中，达特、SAT和VAT与用力肺活量（FVC）的绝对值呈负相关，达特和VAT与一秒用力呼气量（FEV 1）呈负相关。然而，在女性中，达特和VAT（而非SAT）与FVC和FEV 1绝对值呈负相关。总之，使用CT直接测量的腹部脂肪组织的量与肺功能呈负相关。
Although an inverse relationship between abdominal adiposity and pulmonary function has been suggested, direct measurement of abdominal adipose tissue has rarely been attempted. Our object is to determine the impact of abdominal adiposity on pulmonary function by directly measuring abdominal adipose tissue with abdominal computed tomography (CT). In this cross-sectional study, we included never-smokers between the ages of 18 and 85 yr, who had undergone spirometry and abdominal adipose tissue analysis with CT scans during November 1, 2005 to October 31, 2009 as part of the comprehensive health examination. Among a total of 3,469 participants, 890 (25.7%) were male. The mean body mass index and waist circumference among males and females were 24.6 kg/m2 and 87.8 cm and 23.0 kg/m2 and 83.0 cm, respectively. Although total adipose tissue (TAT) of the abdomen in males (269.1 cm2) was similar to that in females (273.6 cm2), the ratio of visceral adipose tissue (VAT)/subcutaneous adipose tissue (SAT) was different; 0.99 in males and 0.50 in females. In males, TAT, SAT, and VAT were inversely associated with the absolute value of forced vital capacity (FVC), and TAT and VAT were inversely associated with forced expiratory volume in one second (FEV1). However, in females, TAT and VAT, but not SAT, were inversely associated with absolute FVC and FEV1 values. In conclusion, the amount of abdominal adipose tissue directly measured using CT is inversely associated with lung function.
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影响因子：
5.8
作者：
Neveu WA;Allard JL;Raymond DM;Bourassa LM;Burns SM;Bunn JY;Irvin CG;Kaminsky DA;Rincon M
通讯作者：
Rincon M
DOI：
10.1038/oby.2010.59
发表时间：
2010-11
期刊：
Obesity (Silver Spring, Md.)
影响因子：
--
作者：
Preis SR;Massaro JM;Robins SJ;Hoffmann U;Vasan RS;Irlbeck T;Meigs JB;Sutherland P;D'Agostino RB Sr;O'Donnell CJ;Fox CS
通讯作者：
Fox CS
影响因子：
4.5
作者：
Lim SY;Rhee EJ;Sung KC
通讯作者：
Sung KC
影响因子：
7.8
作者：
He, Hongbo;Ni, Yinxing;Zhu, Zhiming
通讯作者：
Zhu, Zhiming
DOI：
10.1165/ajrcmb.22.3.3690
发表时间：
2000-03-01
影响因子：
6.4
作者：
Kuhn, C;Homer, RJ;Elias, JA
通讯作者：
Elias, JA