Metal ions in insect reproduction: a crosstalk between reproductive physiology and immunity.

Metal ions in insect reproduction: a crosstalk between reproductive physiology and immunity.
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DOI:
10.1016/j.cois.2022.100924
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发表时间:
2022-08
影响因子:
5.3
通讯作者:
--
中科院分区:
农林科学2区
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--
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大多数昆虫表现出高繁殖能力,这需要大量的能量,包括大量营养素和微量营养素。有趣的是,许多参与卵子发生的蛋白质依赖于金属离子,特别是铁(Fe),锌(Zn)和铜(Cu)。金属离子影响生殖的机制已在果蝇中描述,但在吸血昆虫中仍然知之甚少,其中血液膳食包括大量摄入金属离子。此外,有证据表明,一些参与生殖和免疫的蛋白质可能在这两个过程中具有双重功能。本文综述了金属离子在非吸血昆虫和吸血昆虫生殖中的重要性。此外,我们还讨论了昆虫如何利用参与生殖生理和免疫之间的串扰的蛋白质来优化生理过程,这是一把双刃剑,在分配它们的功能,以保护昆虫和确保繁殖。
Most insects exhibit high reproductive capacity, which demands large amounts of energy, including macronutrients and micronutrients. Interestingly, many proteins involved in oogenesis depend on metals ions, in particular iron (Fe), zinc (Zn), and copper (Cu). Mechanisms by which metal ions influence reproduction have been described in Drosophila melanogaster, but remain poorly understood in hematophagous insects where blood meals include significant ingestion of metal ions. Moreover, there is evidence that some proteins involved in reproduction and immunity could have dual function in both processes. This review highlights the importance of metal ions in the reproduction of nonhematophagous and hematophagous insects. In addition, we discuss how insects optimize physiological processes using proteins involved in crosstalk between reproductive physiology and immunity, which is a double-edge sword in allocating their functions to protect the insect and ensure reproduction.
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