Running speed in mammals increases with muscle n-6 polyunsaturated fatty acid content.

Running speed in mammals increases with muscle n-6 polyunsaturated fatty acid content.
复制标题

哺乳动物的跑步速度随肌肉N-6多不饱和脂肪酸含量而增加。

DOI:
10.1371/journal.pone.0000065
复制
发表时间:
2006-12-20
期刊:
影响因子:
3.7
通讯作者:
Arnold, Walter
Arnold, Walter
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Ruf, Thomas;Valencak, Teresa;Tataruch, Frieda;Arnold, Walter

文献摘要

参考文献

被引文献

相似文献

多不饱和脂肪酸(PUFA)是哺乳动物不能从头合成的重要膳食组分。PUFA,特别是n-3类的PUFA,对动物和人类健康的某些方面的有益作用(例如,心血管功能)是众所周知的。然而,一些观察结果表明,PUFAs也可能影响脊椎动物骨骼肌的性能。例如,实验表明,富含n-6 PUFA的饮食增加了鲑鱼的最大游泳速度。此外,我们最近发现,PUFA的比例在肌肉磷脂的一个非常快的跑步者,棕色的野兔(兔),是非常高的相比,其他哺乳动物。因此,我们预测运动性能,即跑步速度,应该与肌肉脂肪酸谱的差异有关。为了验证这一假设,我们确定了磷脂脂肪酸配置文件的骨骼肌的36种哺乳动物,从鼩到大象。我们发现,确实有一个普遍的积极的,令人惊讶的强关系之间的n-6 PUFAs含量在肌肉磷脂和最大运行速度的哺乳动物。这一发现表明,肌肉脂肪酸组成直接影响高度适应性相关的性状,这可能是动物逃离捕食者或捕获猎物的能力的决定性因素。
Polyunsaturated fatty acids (PUFAs) are important dietary components that mammals cannot synthesize de novo. Beneficial effects of PUFAs, in particular of the n-3 class, for certain aspects of animal and human health (e.g., cardiovascular function) are well known. Several observations suggest, however, that PUFAs may also affect the performance of skeletal muscles in vertebrates. For instance, it has been shown that experimentally n-6 PUFA-enriched diets increase the maximum swimming speed in salmon. Also, we recently found that the proportion of PUFAs in the muscle phospholipids of an extremely fast runner, the brown hare (Lepus europaeus), are very high compared to other mammals. Therefore, we predicted that locomotor performance, namely running speed, should be associated with differences in muscle fatty acid profiles. To test this hypothesis, we determined phospholipid fatty acid profiles in skeletal muscles of 36 mammalian species ranging from shrews to elephants. We found that there is indeed a general positive, surprisingly strong relation between the n-6 PUFAs content in muscle phospholipids and maximum running speed of mammals. This finding suggests that muscle fatty acid composition directly affects a highly fitness-relevant trait, which may be decisive for the ability of animals to escape from predators or catch prey.
DOI: 10.1063/1.1380406
发表时间: 2001-02-01
影响因子: 3.3
作者:
Helge, JW;Wu, BJ;Kiens, B
通讯作者: Kiens, B
DOI: 10.1016/s0305-0491(97)00229-0
发表时间: 1997-11-01
影响因子: 2.2
作者:
Ushio, H;Ohshima, T;Watanabe, T
通讯作者: Watanabe, T
DOI: 10.1007/s11745-006-0162-5
发表时间: 1997-12-01
期刊: LIPIDS
影响因子: 1.9
作者:
Ayre, KJ;Hulbert, AJ
通讯作者: Hulbert, AJ
DOI: 10.33549/physiolres.930792
发表时间: 2006-01-01
影响因子: 2.1
作者:
Nikolaidis, M. G.;Petridou, A.;Mougios, V.
通讯作者: Mougios, V.
DOI: 10.1093/jn/119.3.364
发表时间: 1989-03-01
影响因子: 4.2
作者:
SWANSON, JE;LOKESH, BR;KINSELLA, JE
通讯作者: KINSELLA, JE