New insights on the subcortical representation of reward.
New insights on the subcortical representation of reward.
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DOI：
10.1016/j.conb.2008.07.002
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发表时间：
2008-04
影响因子：
5.7
通讯作者：
Matsumoto, Masayuki
中科院分区：
文献类型：
--
作者：
Hikosaka, Okihide;Bromberg-Martin, Ethan;Hong, Simon;Matsumoto, Masayuki
奖赏信息由许多皮层下区域和神经元类型表示，它们构成了一个复杂的网络。它的输出通常是由基底神经节介导的，在基底神经节中，导致奖励的行为被解除抑制，而导致没有奖励的行为被抑制。中脑多巴胺神经元调节这些基底神经节神经元差异使用相关的奖励预测误差的信号。最近的研究表明，其他类型的皮质下神经元协助，指导，或与多巴胺神经元并行工作。这种与奖励相关的神经元存在于与压力、疼痛、情绪、情感、记忆和唤醒相关的区域。这些结果表明，奖励需要在动物行为的更大框架中理解。
Reward information is represented by many subcortical areas and neuron types, which constitute a complex network. Its output is usually mediated by the basal ganglia where behaviors leading to rewards are disinhibited and behaviors leading to no reward are suppressed. Midbrain dopamine neurons modulate these basal ganglia neurons differentially using signals related to reward-prediction error. Recent studies suggest that other types of subcortical neurons assist, instruct, or work in parallel with dopamine neurons. Such reward-related neurons are found in the areas which have been associated with stress, pain, mood, emotion, memory, and arousal. These results suggest that reward needs to be understood in a larger framework of animal behavior.
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影响因子：
4.8
作者：
Knutson, B;Cooper, JC
通讯作者：
Cooper, JC
影响因子：
4.1
作者：
DEAKIN J F W;GRAEFF F G
通讯作者：
GRAEFF F G
影响因子：
5.3
作者：
Ji, Huifang;Shepard, Paul D.
通讯作者：
Shepard, Paul D.
影响因子：
64.8
作者：
Lauwereyns, J;Watanabe, K;Hikosaka, O
通讯作者：
Hikosaka, O
影响因子：
2
作者：
Kobayashi, Shunsuke;Kawagoe, Reiko;Hikosaka, Okihide
通讯作者：
Hikosaka, Okihide