Photo-Crosslinked Silk Fibroin for 3D Printing.
Photo-Crosslinked Silk Fibroin for 3D Printing.
复制标题
用于3D打印的光交联丝素蛋白。
DOI:
10.3390/polym12122936
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发表时间:
2020-12-09
期刊:
影响因子:
5
通讯作者:
Kaplan DL
中科院分区:
文献类型:
--
作者:
Mu X;Sahoo JK;Cebe P;Kaplan DL
Silk fibroin in material formats provides robust mechanical properties, and thus is a promising protein for 3D printing inks for a range of applications, including tissue engineering, bioelectronics, and bio-optics. Among the various crosslinking mechanisms, photo-crosslinking is particularly useful for 3D printing with silk fibroin inks due to the rapid kinetics, tunable crosslinking dynamics, light-assisted shape control, and the option to use visible light as a biocompatible processing condition. Multiple photo-crosslinking approaches have been applied to native or chemically modified silk fibroin, including photo-oxidation and free radical methacrylate polymerization. The molecular characteristics of silk fibroin, i.e., conformational polymorphism, provide a unique method for crosslinking and microfabrication via light. The molecular design features of silk fibroin inks and the exploitation of photo-crosslinking mechanisms suggest the exciting potential for meeting many biomedical needs in the future.
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影响因子:
5.8
作者:
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通讯作者:
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作者:
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通讯作者:
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DOI:
10.1073/pnas.96.11.6020
发表时间:
1999-05-25
影响因子:
11.1
作者:
Fancy, DA;Kodadek, T
通讯作者:
Kodadek, T