Effects of the Dental Caries Preventive Procedure on the White Spot Lesions during Orthodontic Treatment-An Open Label Randomized Controlled Trial.
Effects of the Dental Caries Preventive Procedure on the White Spot Lesions during Orthodontic Treatment-An Open Label Randomized Controlled Trial.
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DOI：
10.3390/jcm11030854
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发表时间：
2022-02-06
影响因子：
3.9
通讯作者：
Tomonari H
中科院分区：
文献类型：
--
作者：
Shimpo Y;Nomura Y;Sekiya T;Arai C;Okada A;Sogabe K;Hanada N;Tomonari H
(1)背景资料：本研究的目的是评估在固定正畸治疗期间，除氟化物应用外，牙面消毒处理的预防效果。(2)研究方法：对鹤见大学牙科医院正畸科就诊的高龋齿风险患者进行了一项评价龋齿预防程序的开放标签随机对照试验。随访期为6个月。通过定量光诱导荧光（QLF）评价白色斑点病变（WSL）。通过细菌培养监测和评价致龋细菌。此外，通过下一代序列（NGS）评估了口腔微生物组。(3)结果如下：通过混合效应模型，牙齿表面消毒处理显著降低致龋菌和QLF获得的所有参数。(4)结论：牙齿表面消毒处理，除了PMTC和氟化物的应用，是有效的龋齿预防和保持健康的微生物群在正畸治疗。
(1) Background: The aim of this study was to assess the preventive effect of tooth surface disinfection treatment, in addition to fluoride application, during fixed orthodontic treatment. (2) Methods: An open label randomized control trial for the evaluation of the dental caries preventive procedure was performed for the patients with high caries risk who had been visited at Department of Orthodontics, Tsurumi University Dental Hospital for orthodontics treatment. The follow-up period was six months. White spot lesions (WSLs) were evaluated by quantitative light-induced fluorescence (QLF). Cariogenic bacteria were monitored and evaluated by bacterial culture. In addition, the oral microbiome was evaluated by a next-generation sequence (NGS). (3) Results: By the mixed effect modeling, tooth surface disinfection treatment significantly reduced cariogenic bacteria and all parameters obtained by QLF. (4) Conclusions: Tooth surface disinfection treatment, in addition to PMTC and fluoride application, were effective for dental caries prevention and keeping a healthy microbiome during orthodontic treatment.
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