Olfactory function and schizophrenia: an update
Olfactory function and schizophrenia: an update
复制标题
嗅觉功能和精神分裂症:更新
DOI:
--
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发表时间:
2010
影响因子:
6.9
通讯作者:
C. Rupp
中科院分区:
文献类型:
--
作者:
C. Rupp
Purpose of review Olfaction is a field of growing interest in schizophrenia research. This article reviews recent studies on olfactory functions in schizophrenia. Recent findings The current literature provides additional insights into olfactory deficits, abnormalities, and olfactory hedonic dysfunction in schizophrenia. Recent findings reinforce particular associations with negative symptoms and deficit syndrome schizophrenia. Studies indicate that abnormalities in patients with schizophrenia extend to more peripheral olfactory structures and functions, including olfactory receptor neuron dysfunction. Olfactory identification ability was found to relate to prodromal disorganization symptoms in young high-risk patients. Further support for the notion of a genetic contribution to olfactory dysfunction in schizophrenia derives from studies reporting physiological olfactory dysfunction (olfactory event-related potentials) in unaffected relatives, and an odor-specific hyposmia, present in both patients with schizophrenia and family members. Summary Further research is needed to improve our understanding of olfactory dysfunction in schizophrenia. Recent encouraging findings underscore that the olfactory system is a field of research that holds promise for advancing our understanding of the pathophysiology of schizophrenia and possibly as a useful endophenotypic marker of neurodevelopmental vulnerability.
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DOI:
10.1176/jnp.2007.19.2.128
发表时间:
2007
期刊:
The Journal of neuropsychiatry and clinical neurosciences
影响因子:
--
作者:
Kohler,ChristianG;Barrett,FrederickS;Gur,RubenC;Turetsky,BruceI;Moberg,PaulJ
通讯作者:
Moberg,PaulJ
影响因子:
6.6
作者:
B. Turetsky;C. Hahn;Karin E. Borgmann-Winter;P. Moberg
通讯作者:
B. Turetsky;C. Hahn;Karin E. Borgmann-Winter;P. Moberg
DOI:
10.1176/jnp.2006.18.3.389
发表时间:
2006-07
期刊:
The Journal of neuropsychiatry and clinical neurosciences
影响因子:
--
作者:
D. Roalf;B. Turetsky;K. Owzar;Catherine C. Balderston;Sarah C Johnson;C. Brensinger;R. Gur;S. Siegel;P. Moberg
通讯作者:
D. Roalf;B. Turetsky;K. Owzar;Catherine C. Balderston;Sarah C Johnson;C. Brensinger;R. Gur;S. Siegel;P. Moberg
DOI:
--
发表时间:
2001-04
期刊:
Neuropsychiatry, neuropsychology, and behavioral neurology
影响因子:
--
作者:
C. Kohler;P. Moberg;R. Gur;M. O’Connor;M. Sperling;R. Doty
通讯作者:
C. Kohler;P. Moberg;R. Gur;M. O’Connor;M. Sperling;R. Doty
影响因子:
--
作者:
Malaspina, D;Coleman, E
通讯作者:
Coleman, E