Genome-wide association studies for growth traits in broilers.

Genome-wide association studies for growth traits in broilers.
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DOI:
10.1186/s12863-021-01017-7
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发表时间:
2022-01-03
期刊:
影响因子:
1.9
通讯作者:
Zhang H
Zhang H
中科院分区:
生物学3区
文献类型:
--
作者:
Dou D;Shen L;Zhou J;Cao Z;Luan P;Li Y;Xiao F;Guo H;Li H;Zhang H

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生长性状标记和基因的鉴定不仅有利于标记辅助选择/基因组选择,而且还为了解肉鸡生长性状的遗传基础提供重要信息。在本研究中,我们估计了肉鸡八个生长性状的遗传参数,并对这些生长性状进行了全基因组关联研究。多种方法共发现113个QTN,其中ACTA1、IGF2BP1、TAPT1、LDB2、PRKCA、TGFBR2、GLI3、SLC16A7、INHBA、BAMBI、APCDD1、GPR39、GATA4等基因被鉴定为肉鸡快速生长的重要候选基因。这项研究的结果将为了解肉鸡生长性状的遗传基础提供重要信息。在线版本包含可在 10.1186/s12863-021-01017-7 获取的补充材料。
The identification of markers and genes for growth traits may not only benefit for marker assist selection /genomic selection but also provide important information for understanding the genetic foundation of growth traits in broilers. In the current study, we estimated the genetic parameters of eight growth traits in broilers and carried out the genome-wide association studies for these growth traits. A total of 113 QTNs discovered by multiple methods together, and some genes, including ACTA1, IGF2BP1, TAPT1, LDB2, PRKCA, TGFBR2, GLI3, SLC16A7, INHBA, BAMBI, APCDD1, GPR39, and GATA4, were identified as important candidate genes for rapid growth in broilers. The results of this study will provide important information for understanding the genetic foundation of growth traits in broilers. The online version contains supplementary material available at 10.1186/s12863-021-01017-7.
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