The effect of psychosocial factors on breast cancer outcome: a systematic review.
The effect of psychosocial factors on breast cancer outcome: a systematic review.
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DOI：
10.1186/bcr1744
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发表时间：
2007
影响因子：
7.4
通讯作者：
Rafailidis, Petros I.
中科院分区：
文献类型：
--
作者：
Falagas, Matthew E.;Zarkadoulia, Effie A.;Ioannidou, Eleni N.;Peppas, George;Christodoulou, Christos;Rafailidis, Petros I.
我们试图审查现有的证据，心理社会因素对乳腺癌患者的生存的影响。我们系统地检索了PubMed和PsycINFO数据库，以确定相关研究。我们确定了31项研究，检查各种心理社会参数与乳腺癌总生存率/无病生存率的相关性，6项研究检查心理干预是否影响疾病结局。在本综述中总结的31项研究中，25项（80.6%）显示至少一个心理社会变量与疾病结局之间存在统计学显著相关性。与更好的乳腺癌预后相关的参数是社会支持，婚姻，最小化和否认，而抑郁和情绪约束与乳腺癌生存率降低有关;然而，这些因素的作用尚未在所有研究中得到验证。大多数研究表明心理社会因素与生存率之间存在显着关系，但与生存率相关的实际心理社会变量在各研究中并不一致，许多与生存/复发相关的心理社会变量的结果在各研究中并不一致。因此，更多的研究是必要的，关于社会支持，婚姻，最小化和否认，抑郁和情绪约束对乳腺癌生存的作用。
We sought to review the available evidence regarding the effect of psychosocial factors on the survival of breast cancer patients. We systematically searched the PubMed and PsycINFO databases to identify relevant studies. We identified 31 studies examining the association of various psychosocial parameters with overall breast cancer survival/disease free survival and 6 studies examining whether psychological intervention influences the disease outcome. Of the 31 studies summarized in this overview, 25 (80.6%) showed a statistically significant association between at least one psychosocial variable and disease outcome. Parameters associated with better breast cancer prognosis are social support, marriage, and minimizing and denial, while depression and constraint of emotions are associated with decreased breast cancer survival; however, the role of these factors has not been verified in all studies. Most of the studies show a significant relationship between psychosocial factors and survival, but the actual psychosocial variables related to survival are not consistently measured across studies and the findings for many of the psychosocial variables with survival/recurrence are not consistent across studies. Thus, more research is warranted regarding the role of social support, marriage, minimizing and denial, depression and constraint of emotions on breast cancer survival.
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影响因子：
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