Vacuum assisted closure therapy for treatment of complex wounds in replanted extremities
Vacuum assisted closure therapy for treatment of complex wounds in replanted extremities
复制标题
真空辅助闭合疗法治疗再植肢体的复杂伤口
DOI：
10.1002/micr.22178
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发表时间：
2013-11
期刊：
影响因子：
2.1
通讯作者：
Aixi Yu
中科院分区：
文献类型：
--
作者：
Min Zhou;Aixi Yu
本研究的目的是比较真空辅助闭合（VAC）治疗和传统伤口护理与敷料更换治疗上下肢截肢再植患者复杂伤口的结局。回顾性分析2004年5月至2011年12月43例断肢再植患者的临床资料。再植18例18处创面，采用换药治疗，25例26处创面采用VAC治疗。结果通过再植肢体的存活率、肉芽组织的生长、伤口处理与二次手术的间隔时间以及最终的二次伤口覆盖方法来评价。在3例通过换药治疗的患者和5例通过VAC治疗的患者中发现血管血栓形成。两组患者均经抢救性手术后成活。治疗后第6天，常规换药组和VAC组的伤口评分分别为3.6 ± 0.7和5.8 ± 0.7。敷料更换组和VAC组的伤口治疗和二次伤口覆盖手术之间的间隔分别为12.0 ± 1.7天和6.1 ± 0.7天。换药组18例中9例（50.0%）应用皮瓣覆盖创面，VAC组26例中5例（19.2%）应用皮瓣覆盖创面（P < 0.05）。结果表明，VAC可促进创面肉芽组织生长，减少创面覆盖皮瓣的需要，不影响再植成活。© 2013 Wiley Periodicals，Inc.显微外科33：620-624，2013年。
The object of this study was to compare the outcomes of the vacuum assisted closure (VAC) therapy and conventional wound care with dressing change for treatment of complex wounds in patients with replantation of amputated upper and lower extremities. Data of 43 patients with replantation of amputated extremities from May 2004 to December 2011 were reviewed. There were 18 wounds of 18 patients with replantation, which were treated by dressing change and 26 wounds of 25 patients by VAC therapy. The outcomes were evaluated by the survival rate of replanted extremities, growth of granulation tissue, interval between wound treatment and secondary procedure and eventual secondary wound coverage methods. Vascular thromboses were found in 3 patients with wound treatment by dressing change and 5 by VAC. All replants of two groups of patients survived after salvage procedures. The wound score was 3.6 ± 0.7 in the conventional dressing change group and 5.8 ± 0.7 in the VAC group at the sixth day after treatment, respectively. The intervals between wound treatment and secondary wound coverage procedure were 12.0 ± 1.7 days in the dressing change group and 6.1 ± 0.7 days in the VAC group. Flaps were applied for wound coverage in 9 out of 18 (50.0%) wounds in the dressing change group and 5 out of 26 (19.2%) in the VAC group (P < 0.05), when the wounds of rest of patients were covered by the skin graft. The results showed that VAC could promote the growth of granulation tissue of wound, decrease the need of flap for wound coverage, and did not change the survival of replantation. © 2013 Wiley Periodicals, Inc. Microsurgery 33:620–624, 2013.
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影响因子：
2.1
作者：
Lee, Jae Hoon;Chung, Duke Whan;Han, Chung Soo
通讯作者：
Han, Chung Soo
DOI：
10.1046/j.1523-1747.2001.01297.x
发表时间：
2001-04
期刊：
The Journal of investigative dermatology
影响因子：
--
作者：
W. Schmidt;K. Liebold;D. Fassler;U. Wollina
通讯作者：
W. Schmidt;K. Liebold;D. Fassler;U. Wollina
影响因子：
2.8
作者：
C. Lioupis;T. Kotsis;C. Barbatis;E. Seretis;A. Nomikos;Irene Volondakis-Baltatzis;A. Papalois;V. Andrikopoulos;D. Leaper
通讯作者：
C. Lioupis;T. Kotsis;C. Barbatis;E. Seretis;A. Nomikos;Irene Volondakis-Baltatzis;A. Papalois;V. Andrikopoulos;D. Leaper
DOI：
10.1097/ta.0b013e318171971a
发表时间：
2009-03-01
影响因子：
--
作者：
Labler, Ludwig;Rancan, Mario;Keel, Marius
通讯作者：
Keel, Marius
影响因子：
3.1
作者：
Jenwitheesuk, Kamonwan;Surakunprapha, Palakorn;Intanoo, Worawit
通讯作者：
Intanoo, Worawit