Behavior- and Modality-General Representation of Confidence in Orbitofrontal Cortex.
Behavior- and Modality-General Representation of Confidence in Orbitofrontal Cortex.
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DOI：
10.1016/j.cell.2020.05.022
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发表时间：
2020-07-09
期刊：
影响因子：
64.5
通讯作者：
Kepecs A
中科院分区：
文献类型：
--
作者：
Masset P;Ott T;Lak A;Hirokawa J;Kepecs A
Every decision we make is accompanied by a sense of confidence about its likely outcome. This sense informs subsequent behavior, such as investing more—whether time, effort, or money—when reward is more certain. A neural representation of confidence should originate from a statistical computation and predict confidence-guided behavior. An additional requirement for confidence representations to support metacognition is abstraction: they should emerge irrespective of the source of information and inform multiple confidence-guided behaviors. It is unknown if neural confidence signals meet these criteria. Here we show that single orbitofrontal cortex neurons in rats encode statistical decision confidence irrespective of the sensory modality, olfactory or auditory, used to make a choice. The activity of these neurons also predicts two confidence-guided behaviors: trial-by-trial time investment and cross-trial choice strategy updating. Orbitofrontal cortex thus represents decision confidence consistent with a metacognitive process that is useful for mediating confidence-guided economic decisions.
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影响因子：
25
作者：
Fleming SM;van der Putten EJ;Daw ND
通讯作者：
Daw ND
影响因子：
3.4
作者：
Ais, Joaquin;Zylberberg, Ariel;Sigman, Mariano
通讯作者：
Sigman, Mariano
DOI：
10.1073/pnas.1800795115
发表时间：
2018-06-05
影响因子：
11.1
作者：
Bang, Dan;Fleming, Stephen M.
通讯作者：
Fleming, Stephen M.
影响因子：
9.2
作者：
Constantinople, Christine M.;Piet, Alex T.;Brody, Carlos D.
通讯作者：
Brody, Carlos D.
影响因子：
1.9
作者：
Britten, KH;Newsome, WT;Movshon, JA
通讯作者：
Movshon, JA