Measuring the impact of cataract surgery on generic and vision-specific quality of life.

Measuring the impact of cataract surgery on generic and vision-specific quality of life.
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DOI:
10.1007/s11136-012-0270-z
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发表时间:
2013-08
影响因子:
3.5
通讯作者:
Ganiats, Theodore G.
Ganiats, Theodore G.
中科院分区:
医学2区
文献类型:
--
作者:
Groessl, Erik J.;Liu, Lin;Sklar, Marisa;Tally, Steven R.;Kaplan, Robert M.;Ganiats, Theodore G.

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白内障是全球失明的主要原因,并导致美国数百万成年人的视力受损。我们比较了白内障手术前和手术后2个时间点视觉特异性健康相关生活质量(HRQOL)指标与多个通用HRQOL指标的敏感性。参与者在白内障手术前完成了1项视力特异性和5项通用生活质量测量,并在手术后1个月和6个月再次完成。随机效应模型用于测量三个评估点的变化。NEI-VFQ 25总分和所有11个分量表在第一个间隔(基线和1个月)内均显示出显着改善。在第二个间隔期间(术后1个月至6个月),观察到总分和11个NEI-VEGF 25分量表中的5个显著改善。在第一个时间间隔内,一些基于偏好的通用HRQOL指标的HRQOL显著增加,但第二个时间间隔内的变化大多不显著。SF-36 v2 ™或SF 6D量表在任何评估期之间均无显著变化。NEI-VEGF 25对视觉特异性QOL领域的变化敏感。一些基于偏好的通用HRQOL指标对变化也很敏感,并显示出与NEI-VQOL 25的收敛性,但影响很小。SF-36 v2 ™和SF-6D没有以类似的方式变化,可能反映了缺乏视觉相关内容。试图记录白内障手术的视觉特异性和一般HRQOL改善的研究在选择测量方法时应考虑这些结果。
Cataracts are the leading cause of blindness worldwide and cause visual impairment for millions of adults in the US. We compared the sensitivity of a vision-specific health-related quality of life (HRQOL) measure to that of multiple generic measures of HRQOL before and at 2 two points after cataract surgery. Participants completed 1 vision-specific and 5 generic quality of life measures before cataract surgery, and again 1-month, and 6-months after surgery. Random effects modeling was used to measure changes over the three assessment points. The NEI-VFQ25 total score and all 11 subscales showed significant improvements during the first interval (baseline and 1-month). During the second interval (1-month to 6-months post-surgery), significant improvements were observed on the total score and 5 of 11 NEI-VFQ25 subscales. There were significant increases in HRQOL during the first interval on some preference-based generic HRQOL measures, though changes during the second interval were mostly non-significant. None of the SF-36v2™ or SF6D scales changed significantly between any of the assessment periods. The NEI-VFQ25 was sensitive to changes in vision-specific domains of QOL. Some preference-based generic HRQOL measures were also sensitive to change and showed convergence with the NEI-VFQ25, but the effects were small. The SF-36v2™ and SF-6D did not change in a similar manner, possibly reflecting a lack of vision-related content. Studies seeking to document both the vision-specific and generic HRQOL improvements of cataract surgery should consider these results when selecting measures.
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