Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading.
Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading.
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DOI：
10.1002/jor.20938
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发表时间：
2009-12
影响因子：
2.8
通讯作者：
Soslowsky, Louis J.
中科院分区：
文献类型：
--
作者：
Lake, Spencer P.;Miller, Kristin S.;Elliott, Dawn M.;Soslowsky, Louis J.
关键词：
肌腱表现出非线性的应力-应变行为，这可能部分是由于胶原纤维通过细胞外基质的运动。虽然已经开发了一些技术来评估其他软组织的纤维结构，但肌腱在载荷下的组织行为尚未确定。冈上肌腱（SST）的肩袖是特别感兴趣的调查，由于其复杂的力学环境和相应的不均匀性。此外，SST损伤经常发生，治疗策略的成功有限，说明需要更好地了解SST的属性。因此，本研究的目的是定量评估不均匀的拉伸力学性能，纤维组织和纤维的重新排列下的负载下的人类SST利用一种新的偏振光技术。纤维分布被发现在负载下变得更加对齐，特别是在低刚度趾区域，这表明纤维重新排列可能是部分负责观察到的非线性行为。纤维排列被发现与力学参数显着相关，提供了证据，在肌腱强的结构-功能关系。人类SST表现出复杂的，不均匀的力学性能和纤维分布，可能是由于其复杂的加载环境。令人惊讶的是，变性的组织学等级与机械性能无关。
Tendon exhibits nonlinear stress-strain behavior that may be due, in part, to movement of collagen fibers through the extracellular matrix. While a few techniques have been developed to evaluate the fiber architecture of other soft tissues, the organizational behavior of tendon under load has not been determined. The supraspinatus tendon (SST) of the rotator cuff is of particular interest for investigation due to its complex mechanical environment and corresponding inhomogeneity. In addition, SST injury occurs frequently with limited success in treatment strategies, illustrating the need for a better understanding of SST properties. Therefore, the objective of this study was to quantitatively evaluate the inhomogeneous tensile mechanical properties, fiber organization and fiber realignment under load of human SST utilizing a novel polarized light technique. Fiber distributions were found to become more aligned under load, particularly during the low stiffness toe-region, suggesting that fiber realignment may be partly responsible for observed nonlinear behavior. Fiber alignment was found to correlate significantly with mechanical parameters, providing evidence for strong structure-function relationships in tendon. Human SST exhibits complex, inhomogeneous mechanical properties and fiber distributions, perhaps due to its complex loading environment. Surprisingly, histological grade of degeneration did not correlate with mechanical properties.
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DOI：
10.1115/1.1427698
发表时间：
2002-02-01
影响因子：
1.7
作者：
Hansen, KA;Weiss, JA;Barton, JK
通讯作者：
Barton, JK
影响因子：
--
作者：
Morgan, Mary;Kostyuk, Oksana;Mudera, Vivek
通讯作者：
Mudera, Vivek
影响因子：
2.9
作者：
Hurschler, C;Provenzano, PP;Vanderby, R
通讯作者：
Vanderby, R
影响因子：
2.4
作者：
Guerin, Heather Anne L.;Elliott, Dawn M.
通讯作者：
Elliott, Dawn M.
DOI：
10.1115/1.2798026
发表时间：
1998-08-01
影响因子：
1.7
作者：
Dickey, JP;Hewlett, BR;Bednar, DA
通讯作者：
Bednar, DA