Inhibitory effects of ginseng seed on melanin biosynthesis.
Inhibitory effects of ginseng seed on melanin biosynthesis.
复制标题
人参籽对黑色素生物合成的抑制作用。
DOI：
10.4103/0973-1296.133271
复制
发表时间：
2014-04
影响因子：
0.7
通讯作者：
Choi SY
中科院分区：
文献类型：
--
作者：
Lee Y;Kim KT;Kim SS;Hur J;Ha SK;Cho CW;Choi SY
人参根在韩国传统上被用于治疗许多疾病。然而，到目前为止，人参种子大多未被使用和丢弃。作为我们正在进行的人参籽研究的一部分，人参籽对黑色素产生的抑制作用被验证，以评估其作为皮肤脱色物质的潜力。本研究通过酪氨酸酶抑制作用检测人参籽对黑色素生成的抑制作用，并分析人参籽对黑色素a细胞黑色素生成的影响。将人参种子的乙醇提取物以100 ppm的浓度施加到黑色素a细胞，黑色素产生减少了35.1%，而没有细胞毒性。此外，人参籽的乙醇提取物显示出降低酪氨酸酶活性。与熊果苷、人参叶和人参根的乙醇提取物在相同浓度下的黑色素抑制活性相比，结果显示出优异的黑色素抑制活性，因此可以得出结论，人参籽显示出作为皮肤脱色物质的巨大潜力。
Ginseng root has been traditionally used for the treatment of many diseases in Korea. However, so far ginseng seed has been mostly unused and discarded. As part of our ongoing research on the ginseng seeds, the inhibitory effect of ginseng seeds on melanin production was verified to assess their potential as a skin depigmenting substance. The present study measured the inhibitory effect of ginseng seeds on melanin production through the tyrosinase inhibitory effect and analyzed their effects on melanin production in melan-a-cells. Ethanol extract of ginseng seed was applied to melan-a-cells at a concentration of 100 ppm and melanin production was reduced by 35.1% without cytotoxicity. In addition, the ethanol extract of ginseng seed was shown to reduce tyrosinase activity. Because the results showed excellent melanin inhibitory activity compared with that obtained by arbutin, ethanol extracts of ginseng leaf and ginseng root at the same concentration, it can be concluded that ginseng seeds show great potential as a skin depigmenting substance.
登录
查看更多内容
影响因子：
2
作者：
Im, SJ;Kim, KN;Woo, WH
通讯作者：
Woo, WH
影响因子：
6.3
作者：
Song M;Mun JH;Ko HC;Kim BS;Kim MB
通讯作者：
Kim MB
影响因子：
6.3
作者：
Kim DH
通讯作者：
Kim DH
DOI：
10.1006/bbrc.1998.8169
发表时间：
1998-02-24
影响因子：
3.1
作者：
Shin, NH;Ryu, SY;Kim, Y
通讯作者：
Kim, Y
影响因子：
6.3
作者：
Choi SY;Cho CW;Lee Y;Kim SS;Lee SH;Kim KT
通讯作者：
Kim KT