Associations between prenatal and infancy weight gain and BMI, fat mass, and fat distribution in young adulthood: a prospective cohort study in males and females born very preterm.
Associations between prenatal and infancy weight gain and BMI, fat mass, and fat distribution in young adulthood: a prospective cohort study in males and females born very preterm.
复制标题
产前和婴儿期体重增加与成年早期体重指数、脂肪量和脂肪分布之间的关联：一项针对早产男性和女性的前瞻性队列研究。
DOI：
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发表时间：
2005
影响因子：
7.1
通讯作者：
F. Dekker
中科院分区：
文献类型：
--
作者：
A. M. Euser;M. Finken;M. Keijzer;E. Hille;J. Wit;F. Dekker
背景
越来越多的证据表明，成人的身体组成与产前和婴儿期体重增加有关，但不同时期的相对重要性尚未阐明。
目的
目的是研究出生前、出生后早期和婴儿后期体重增加与体重指数（BMI）、脂肪量和年轻成年期脂肪分布之间的关系。
设计
我们纳入了403名来自荷兰国家前瞻性随访研究的19岁男性和女性，他们出生于妊娠<32周。研究了19岁时BMI、腰围、腰臀比SD评分和肩胛下肱三头肌比、体脂百分比、脂肪量和去脂肪量与出生体重SD评分、早产至产后3个月体重增加（产后早期体重增加）和产后3个月至1年体重增加（婴儿晚期体重增加）的关系。
结果
出生体重SD评分与体重、身高、BMI SD评分和19岁时的无脂肪质量呈正相关，但与脂肪质量、体脂百分比或脂肪分布无关。产后早期和婴儿晚期的体重增加与成人身高、体重、BMI、腰围SD评分、脂肪质量、无脂肪质量和体脂百分比正相关，但与腰臀比SD评分或肩胛下-三头肌比率无关。
结论
在极早产儿中，妊娠32周前的体重增加与成人体型呈正相关，但与身体成分和脂肪分布无关。出生后早期体重增加和婴儿后期体重增加（程度较轻）与19岁时BMI SD评分和体脂百分比较高以及腹部脂肪较多相关。
BACKGROUND
Increasing evidence indicates that adult body composition is associated with prenatal and infancy weight gain, but the relative importance of different time periods has not been elucidated.
OBJECTIVE
The objective was to study the association between prenatal, early postnatal, and late infancy weight gain and body mass index (BMI), fat mass, and fat distribution in young adulthood.
DESIGN
We included 403 men and women aged 19 y from a Dutch national prospective follow-up study who were born at <32 wk of gestation. BMI, waist circumference, and waist-to-hip ratio SD scores and subscapular-to-triceps ratio, percentage body fat, fat mass, and fat-free mass at age 19 y were studied in relation to birth weight SD scores, weight gain from preterm birth until 3 mo postterm (early postnatal weight gain), and weight gain from 3 mo until 1 y postterm (late infancy weight gain).
RESULTS
Birth weight SD scores were positively associated with weight, height, BMI SD scores, and fat-free mass at age 19 y but not with fat mass, percentage body fat, or fat distribution. Early postnatal and late infancy weight gain were positively associated with adult height, weight, BMI, waist circumference SD scores, fat mass, fat-free mass, and percentage body fat but not with waist-to-hip ratio SD scores or subscapular-to-triceps ratio.
CONCLUSIONS
In infants born very preterm, weight gain before 32 wk of gestation is positively associated with adult body size but not with body composition and fat distribution. More early postnatal and, to a lesser extent, late infancy weight gain are associated with higher BMI SD scores and percentage body fat and more abdominal fat at age 19 y.
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影响因子：
37.8
作者：
Curhan, GC;Chertow, GM;Stampfer, MJ
通讯作者：
Stampfer, MJ
影响因子：
37.8
作者：
Curhan, GC;Willett, WC;Stampfer, MJ
通讯作者：
Stampfer, MJ
影响因子：
5.1
作者：
Peralta-Carcelen, M;Jackson, DS;Nelson, KG
通讯作者：
Nelson, KG
影响因子：
5
作者：
Pietiläinen, KH;Kaprio, J;Rose, RJ
通讯作者：
Rose, RJ