Lymphoblastoid cell lines and burkitt‐lymphoma‐derivee cell lines differ in the expression of a second epstein‐barr virus encoded nuclear antigen

Lymphoblastoid cell lines and burkitt‐lymphoma‐derivee cell lines differ in the expression of a second epstein‐barr virus encoded nuclear antigen
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类淋巴母细胞系和伯基特淋巴瘤衍生细胞系在第二种 EB 病毒编码的核抗原的表达上存在差异

DOI:
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发表时间:
1986
影响因子:
6.4
通讯作者:
G. Klein
G. Klein
中科院分区:
医学1区
文献类型:
--
作者:
I. Ernberg;B. Kallin;J. Dillner;K. Falk;B. Ehlin‐Henriksson;M. Hammarskjöld;G. Klein

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Twenty‐seven Epstein‐Barr virus (EBV)‐transformed lymphoblastoid cell lines and 27 EBV‐carrying Bur‐kitt‐lymphoma‐derived lines were analyzed for expression of the second EBV‐encoded nuclear antigen (EBNA‐2) by immunoblotting and anticomple‐ment immunofluorescence with EBNA‐2‐specific sera. While all lymphoblastoid cell lines expressed EBNA‐2, only 10 of the 27 BL lines were EBNA‐2‐positive. Comparison of the EBNA‐2 coding Bam HI W‐Y‐ and H‐fragments of EBV‐DNA in the different cell lines by restriction enzyme analysis suggests that EBNA‐2 negativity is due either to sequence diversity or to a deletion in the BamHI WYH region.
DOI: 10.1073/pnas.81.23.7632
发表时间: 1984-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
DAMBAUGH, T;HENNESSY, K;KIEFF, E
通讯作者: KIEFF, E
四种病毒确定的核抗原在 Epstein-Barr 病毒转化细胞中表达。
DOI: 10.1073/pnas.83.5.1499
发表时间: 1986
影响因子: 11.1
作者:
Kallin,B;Dillner,J;Ernberg,I;Ehlin-Henriksson,B;Rosén,A;Henle,W;Henle,G;Klein,G
通讯作者: Klein,G
转移 3.4 兆道尔顿 Epstein-Barr 病毒 DNA 克隆片段后,小鼠细胞中核新抗原稳定表达。
DOI: 10.1073/pnas.79.18.5688
发表时间: 1982
影响因子: 11.1
作者:
Summers,WP;Grogan,EA;Shedd,D;Robert,M;Liu,CR;Miller,G
通讯作者: Miller,G
第二个核蛋白是由潜伏感染的 Epstein-Barr 病毒编码的。
DOI: 10.1126/science.2983420
发表时间: 1985
期刊: Science (New York, N.Y.)
影响因子: --
作者:
Hennessy,K;Kieff,E
通讯作者: Kieff,E
用病毒基因组的克隆片段进行基因转移后,小鼠细胞中第二个 Epstein-Barr 病毒确定的核抗原的表达。
DOI: 10.1073/pnas.82.10.3435
发表时间: 1985
影响因子: 11.1
作者:
Rymo,L;Klein,G;Ricksten,A
通讯作者: Ricksten,A