Burden of anemia and its underlying causes in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019.
Burden of anemia and its underlying causes in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019.
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DOI：
10.1186/s13045-021-01202-2
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发表时间：
2021-11-04
影响因子：
28.5
通讯作者：
Grieger JA
中科院分区：
文献类型：
--
作者：
Safiri S;Kolahi AA;Noori M;Nejadghaderi SA;Karamzad N;Bragazzi NL;Sullman MJM;Abdollahi M;Collins GS;Kaufman JS;Grieger JA
贫血是一种常见疾病，影响约40%的儿童和30%的育龄妇女，并可能造成严重的健康后果。本研究报告了1990年至2019年期间全球，区域和国家贫血负担及其根本原因，按年龄，性别和社会人口指数（SDI）。关于点患病率和残疾生活年（YLD）的公开数据来自1990年至2019年期间204个国家和地区的全球疾病负担（GBD）2019研究。列出了每100，000人的点患病率、YLD计数和发生率，沿着列出了其相应的95%不确定性区间。2019年，全球贫血的年龄标准化点患病率和YLD率分别为每10万人口23，176.2（22，943.5 - 23，418.6）和672.4（447.2-981.5）。此外，在1990-2019年期间，全球年龄标准化点患病率和YLD率分别下降了13.4%（12.1-14.5%）和18.8%（16.9-20.8%）。贫血的国家点患病率最高的是赞比亚[49327.1（95% UI：46，838.5 - 51，700.1）]、马里[46890.1（95% UI：44，301.1 - 49，389.8）]和布基纳法索[46117.2（95% UI：43，640.7 - 48，319.2）]。2019年，全球贫血的点患病率分别在15-19岁和95岁以上年龄组的女性和男性中最高。此外，贫血负担在社会经济发展较高的地区较低。在全球范围内，大多数流行病例可归因于膳食缺铁，以及血红蛋白病和溶血性贫血。贫血仍然是一个主要的健康问题，特别是在欠发达国家的女性中。应考虑实施预防方案，重点是改善铁补充剂的获得、血红蛋白病的早期诊断和治疗。在线版本包含补充材料，可通过10.1186/s13045-021-01202-2获得。
Anemia is a common disease which affects around 40% of children and 30% of reproductive age women and can have major health consequences. The present study reports the global, regional and national burden of anemia and its underlying causes between 1990 and 2019, by age, sex and socio-demographic index (SDI). Publicly available data on the point prevalence and years lived with disability (YLDs) were retrieved from the global burden of disease (GBD) 2019 study for 204 countries and territories between 1990 and 2019. The point prevalence, YLD counts and rates per 100,000 population were presented, along with their corresponding 95% uncertainty intervals. In 2019, the global age-standardized point prevalence and YLD rates for anemia were 23,176.2 (22,943.5–23,418.6) and 672.4 (447.2–981.5) per 100,000 population, respectively. Moreover, the global age-standardized point prevalence and YLD rate decreased by 13.4% (12.1–14.5%) and 18.8% (16.9–20.8%), respectively, over the period 1990–2019. The highest national point prevalences of anemia were found in Zambia [49327.1 (95% UI: 46,838.5–51,700.1)], Mali [46890.1 (95% UI: 44,301.1–49,389.8)], and Burkina Faso [46117.2 (95% UI: 43,640.7–48,319.2)]. In 2019, the global point prevalence of anemia was highest in the 15–19 and 95+ age groups in females and males, respectively. Also, the burden of anemia was lower in regions with higher socio-economic development. Globally, most of the prevalent cases were attributable to dietary iron deficiency, as well as hemoglobinopathies and hemolytic anemias. Anemia remains a major health problem, especially among females in less developed countries. The implementation of preventive programs with a focus on improving access to iron supplements, early diagnosis and the treatment of hemoglobinopathies should be taken into consideration. The online version contains supplementary material available at 10.1186/s13045-021-01202-2.
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