Improved Corrosion Behavior and Biocompatibility of Porous Titanium Samples Coated with Bioactive Chitosan-Based Nanocomposites.
Improved Corrosion Behavior and Biocompatibility of Porous Titanium Samples Coated with Bioactive Chitosan-Based Nanocomposites.
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DOI：
10.3390/ma14216322
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发表时间：
2021-10-22
期刊：
影响因子：
--
通讯作者：
Martín-Pedrosa F
中科院分区：
文献类型：
--
作者：
García-Cabezón C;Godinho V;Salvo-Comino C;Torres Y;Martín-Pedrosa F
多孔钛种植体可以很好的解决应力遮挡现象。然而，孔隙的存在损害了机械和耐腐蚀性。在这项工作中，多孔钛样品获得使用空间持有人的技术与壳聚糖，壳聚糖/银纳米粒子和壳聚糖/羟基磷灰石涂层使用只有一个步骤和经济的电沉积方法。分析了涂层的形貌、均匀性和化学成分。研究了孔隙率和涂层类型对耐腐蚀性和细胞行为的影响。电化学研究表明，多孔样品显示出高电流密度和不稳定的氧化膜，因此，有必要进行表面处理，以提高耐腐蚀性。壳聚糖涂层提供了显着的耐腐蚀性的改善，但壳聚糖/AgNPs和壳聚糖/HA涂层显示出最高的保护效率，特别是对于更多的多孔样品。此外，这些涂层具有比壳聚糖涂层更好的粘附性，并且获得的更高的表面粗糙度有利于细胞粘附和增殖。最后，涂层和多孔基质材料的组合具有最佳的生物力学平衡和生物功能行为，提出了作为一个潜在的候选人，用于替换小的，受损的骨组织。
Porous titanium implants can be a good solution to solve the stress shielding phenomenon. However, the presence of pores compromises mechanical and corrosion resistance. In this work, porous titanium samples obtained using a space-holder technique are coated with Chitosan, Chitosan/AgNPs and Chitosan/Hydroxyapatite using only one step and an economic electrodeposition method. The coatings’ topography, homogeneity and chemical composition were analyzed. A study of the effect of the porosity and type of coating on corrosion resistance and cellular behavior was carried out. The electrochemical studies reveal that porous samples show high current densities and an unstable oxide film; therefore, there is a need for surface treatments to improve corrosion resistance. The Chitosan coatings provide a significant improvement in the corrosion resistance, but the Chitosan/AgNPs and Chitosan/HA coatings showed the highest protection efficiency, especially for the more porous samples. Furthermore, these coatings have better adherence than the chitosan coatings, and the higher surface roughness obtained favors cell adhesion and proliferation. Finally, a combination of coating and porous substrate material with the best biomechanical balance and biofunctional behavior is proposed as a potential candidate for the replacement of small, damaged bone tissues.
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影响因子：
2.9
作者：
Civantos, Ana;Giner, Merce;Torres, Yadir
通讯作者：
Torres, Yadir
影响因子：
5.4
作者：
Civantos, Ana;Dominguez, Cristina;Torres, Yadir
通讯作者：
Torres, Yadir
影响因子：
4.6
作者：
Jablonski, P.;Hebda, M.;Kyziol, K.
通讯作者：
Kyziol, K.
影响因子：
2.9
作者：
Giner, Merce;Olmo, Alberto;Torres, Yadir
通讯作者：
Torres, Yadir
影响因子：
5.4
作者：
Dominguez-Trujillo, Cristina;Ternero, Fatima;Torres, Yadir
通讯作者：
Torres, Yadir