Molecular mechanisms at the core of the plant circadian oscillator.

Molecular mechanisms at the core of the plant circadian oscillator.
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DOI:
10.1038/nsmb.3327
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发表时间:
2016-12
影响因子:
16.8
通讯作者:
Kay SA
Kay SA
中科院分区:
生物学1区
文献类型:
--
作者:
Nohales MA;Kay SA

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生物钟是内源性的计时网络,允许生物体将其生理与其不断变化的环境保持一致,并在一天和一年中最相关的时间进行生物过程。振荡器的初始反馈回路模型已经被新出现的证据所丰富,这些证据强调了有助于产生节律的越来越多的因素和机制。在这篇综述中,我们考虑了两个主要的输入途径,连接的模式植物拟南芥的生物钟,其环境和讨论的最新进展,了解如何转录,翻译后和转录后机制有助于时钟功能。
Circadian clocks are endogenous timekeeping networks that allow organisms to align their physiology with their changing environment and to perform biological processes at the most relevant times of the day and year. Initial feedback-loop models of the oscillator have been enriched by emerging evidence highlighting the increasing variety of factors and mechanisms that contribute to the generation of rhythms. In this Review, we consider the two major input pathways that connect the circadian clock of the model plant Arabidopsis thaliana to its environment and discuss recent advances in understanding of how transcriptional, post-translational and post-transcriptional mechanisms contribute to clock function.
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