Victims of war-Psychoendocrine evidence for the impact of traumatic stress on psychological well-being of adolescents growing up during the Israeli-Palestinian conflict.
Victims of war-Psychoendocrine evidence for the impact of traumatic stress on psychological well-being of adolescents growing up during the Israeli-Palestinian conflict.
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战争受害者——心理内分泌证据表明创伤性压力对以色列-巴勒斯坦冲突期间成长的青少年心理健康的影响
DOI：
10.1111/psyp.13271
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Kirschbaum
中科院分区：
文献类型：
--
作者：
Shaheen;Schindler;Saar-Ashkenazy;Bani Odeh;Friedman;Kirschbaum
暴力冲突是严重的创伤性压力源，对身心健康产生有害影响，儿童和青少年尤其面临风险。对于下丘脑-垂体-肾上腺（HPA）轴，创伤暴露个体的失调模式已被证实。这项研究旨在调查在以色列-巴勒斯坦冲突期间成长的巴勒斯坦青少年自我报告的心理健康状况。头发皮质醇浓度（HCC）作为长期HPA轴畸变的心理内分泌标志物，沿着潜在的保护因素相干感（SoC;即，将世界和新出现的压力源解释为可理解、可管理和有意义的全球心态）。在2014年至2016年期间，对来自西岸的233名11至16岁的青少年进行了创伤后应激障碍（PTSD），抑郁，焦虑，HCC和SoC检查。超过一半的参与者报告了创伤暴露，其中40%符合初步PTSD诊断的标准，焦虑和抑郁的患病率很高。与未暴露于任何创伤事件的亚组相比，PTSD亚组中的HCC显著升高（p= 0.046），创伤暴露个体介于两者之间。HCC还与创伤应激的典型后遗症相关。值得注意的是，SoC与自我报告的精神病理学以及创伤组中的HCC呈负相关。研究结果说明了青少年暴露于慢性创伤性应激的情况，并扩展了在这种条件下HPA轴功能异常的文献。他们还指出了SoC的核心作用，这可能意味着新的战略，以帮助个人暴露于持续的冲突。
Violent conflicts are severe traumatic stressors with detrimental effects on physical and mental health, with children and adolescents being particularly at risk. For the hypothalamic–pituitary–adrenal (HPA) axis, characteristic patterns of dysregulation in trauma‐exposed individuals have been shown. This study set out to investigate self‐reported mental well‐being in Palestinian adolescents growing up during the Israeli–Palestinian conflict. Hair cortisol concentrations (HCC) as a psychoendocrine marker for long‐term HPA axis aberrations along with the potential protective factor sense of coherence (SoC; i.e., the global mindset to interpret the world and emerging stressors as comprehensible, manageable, and meaningful) were examined. Between 2014 and 2016, posttraumatic stress disorder (PTSD), depression, anxiety, HCC, and SoC were examined in 233 adolescents aged 11 to 16 from the West Bank. More than half of the participants reported trauma exposure, with 40% fulfilling the criteria of a preliminary PTSD diagnosis and a high prevalence of anxiety and depression. HCC was significantly elevated in the PTSD subgroup compared to the subgroup not exposed to any traumatic events (p= 0.046), with trauma‐exposed individuals in between. HCC was further associated with typical sequelae of traumatic stress. Notably, SoC was inversely related to self‐reported psychopathology, as well as to HCC in the trauma group. The results illustrate the situation of adolescents exposed to chronic traumatic stress and extend the literature on aberrant HPA axis functioning under such conditions. They also point out a central role of SoC, which may imply new strategies to aid individuals exposed to ongoing conflicts.
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影响因子：
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作者：
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通讯作者：
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