Clinical evaluation of fenestration decompression combined with secondary curettage for ameloblastoma of the jaw: retrospective radiographic analysis.
Clinical evaluation of fenestration decompression combined with secondary curettage for ameloblastoma of the jaw: retrospective radiographic analysis.
复制标题
DOI：
10.1186/s12903-022-02474-x
复制
发表时间：
2022-10-14
期刊：
影响因子：
2.9
通讯作者：
He, Jie
中科院分区：
文献类型：
--
作者：
Wu, Kailiu;Luo, Hao;Yuan, Zhuang;Wang, Yanan;Qin, Xing;He, Jie
成釉细胞瘤是一种良性牙源性上皮肿瘤，局部浸润，复发率高，最常见于颌骨。本研究的目的是探讨开窗减压联合二次刮宫术（FDSC）手术治疗颌骨成釉细胞瘤的效果，并阐明FDSC成为大病灶成釉细胞瘤合适治疗方法的可能性。 对 145 例诊断为多囊性成釉细胞瘤 (MA) 的患者和 88 例诊断为单囊性成釉细胞瘤 (UA) 的患者进行了回顾性分析。根据治疗方案将这些患者分为两组：FDSC 组和局部刮除（LC）组。刮宫术后2年进行全景X线检查，评价各例病灶面积的变化，并通过卡方检验进一步评估不同治疗方法的治疗效果。对于MA，FDSC组囊腔面积缩小有效率（71.19%）高于LC组（30.23%）（P < 0.001）。对于UA患者，FDSC术后病灶面积缩小有效率达93.02%，高于LC术后的53.33%（P < 0.001）。此外，FDSC组MA复发率为30.51%，与LC组有显着性差异（P<0.001）。 UA方面，FDSC和LC术后复发率分别为13.95%和28.89%，两组间差异无统计学意义（P > 0.05）。 FDSC在MA和UA中均表现出比LC更好的疗效，而这两种治疗策略在UA中的复发率没有显着差异。上述数据表明，FDSC可作为大病灶MA或UA患者常规、安全、有效、适宜的手术治疗方案。
Ameloblastoma is a benign odontogenic epithelial tumor with local infiltration and a high recurrence rate that occurs most frequently in the jawbone. The aim of this study was to investigate the outcomes of fenestration decompression combined with secondary curettage (FDSC) in the surgical treatment of jaw ameloblastoma, and clarify the possibility of FDSC to become an appropriate therapeutic method for ameloblastoma with large lesion. A retrospective analysis was carried out in 145 patients diagnosed with multicystic ameloblastoma (MA) and 88 patients with unicystic ameloblastoma (UA). These patients were divided into two groups based on the therapeutic regimen: the FDSC group and the local curettage (LC) group. Panoramic radiography was taken 2 years after curettage to evaluate the change in lesion area in each case, and the therapeutic effects of different treatment methods were further assessed by the chi square test. For MA, the effective rate of cystic cavity area reduction in the FDSC group (71.19%) was higher than that in the LC group (30.23%) (P < 0.001). For UA patients, the effective rate of lesion area reduction after FDSC was 93.02%, which was higher than that after LC (53.33%) (P < 0.001). Moreover, the recurrence rate of the FDSC group in the MA was 30.51%, which was significantly different from that of the LC group (P < 0.001). Regarding UA, the recurrence rates were 13.95% and 28.89%, after FDSC and LC, respectively, with no significant differences between the two groups (P > 0.05). FDSC exhibits a much better curative effect than LC in both MA and UA, whereas the recurrence rate of these two therapeutic strategies did not significantly differ in UA. The above data demonstrated that FDSC may serve as a routine, safe, effective and appropriate surgical treatment plan for MA or UA patients with large lesions.
登录
查看更多内容
影响因子：
5.2
作者：
Russo D;Mariani P;Caponio VCA;Lo Russo L;Fiorillo L;Zhurakivska K;Lo Muzio L;Laino L;Troiano G
通讯作者：
Troiano G
影响因子：
3.8
作者：
Ledesma-Montes, C.;Mosqueda-Taylor, A.;Meneses-Garcia, A.
通讯作者：
Meneses-Garcia, A.
影响因子：
2.5
作者：
Datta, R;Winston, JS;Hicks, WL
通讯作者：
Hicks, WL
DOI：
10.1016/j.bjoms.2016.07.017
发表时间：
2016-11-01
影响因子：
1.8
作者：
Haq, Jahrad;Siddiqui, Sarah;McGurk, Mark
通讯作者：
McGurk, Mark
下颌大囊性病变减压后下牙槽神经功能恢复
影响因子：
3.8
作者：
Liang, Y-j;He, W-j;Liao, G-q
通讯作者：
Liao, G-q