The compressed breast during mammography and breast tomosynthesis: in vivo shape characterization and modeling.
The compressed breast during mammography and breast tomosynthesis: in vivo shape characterization and modeling.
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DOI：
10.1088/1361-6560/aa7cd0
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发表时间：
2017-08-07
影响因子：
3.5
通讯作者：
Sechopoulos I
中科院分区：
文献类型：
--
作者：
Rodríguez-Ruiz A;Agasthya GA;Sechopoulos I
表征和开发基于患者的受压乳房 3D 模型，进行乳房 X 线摄影和乳房断层合成。在这项经 IRB 批准、符合 HIPAA 标准的研究中，招募了 50 名女性，在乳房压缩期间使用结构光 (SL) 进行 3D 乳房表面成像，同时采集断层合成图像。使用一对 SL 系统来获取 3D 表面图像，方法是将 24 种不同的图案投影到受压的乳房上，并在大约 12 – 16 秒内捕获它们在乳房表面的反射。通过主成分分析对 3D 表面进行表征和建模。将所得表面模型与先前开发的投影压缩乳房形状的 2D 模型相结合，生成完整的 3D 模型。由于图像采集过程中的技术问题，十名患者的数据被丢弃。最大乳房厚度（在胸壁处）的平均值为 56 毫米，向乳头方向减少 13%（乳房倾斜角度为 5.2°）。未与压迫板或支撑台接触的乳房部分平均延伸 17 毫米，即胸壁到乳头距离的 18%。沿乳房表面的最外点位于总厚度中线下方。创建了压缩乳房形状的完整 3D 模型，并将其实现为可供下载的软件应用程序，能够生成正在压缩的乳房的新的随机逼真 3D 形状。实现了乳房曲率和形状的准确表征和建模，并将用于各种图像处理和临床任务。
To characterize and develop a patient-based 3D model of the compressed breast undergoing mammography and breast tomosynthesis. During this IRB-approved, HIPAA-compliant study, 50 women were recruited to undergo 3D breast surface imaging with structured light (SL) during breast compression, along with simultaneous acquisition of a tomosynthesis image. A pair of SL systems were used to acquire 3D surface images by projecting 24 different patterns onto the compressed breast and capturing their reflection off the breast surface in approximately 12 – 16 seconds. The 3D surface was characterized and modeled via principal component analysis. The resulting surface model was combined with a previously developed 2D model of projected compressed breast shapes to generate a full 3D model. Data from ten patients were discarded due to technical problems during image acquisition. The maximum breast thickness (found at the chest-wall) had an average value of 56 mm, and decreased 13% towards the nipple (breast tilt angle of 5.2°). The portion of the breast not in contact with the compression paddle or the support table extended on average 17 mm, 18% of the chest-wall to nipple distance. The outermost point along the breast surface lies below the midline of the total thickness. A complete 3D model of compressed breast shapes was created and implemented as a software application available for download, capable of generating new random realistic 3D shapes of breasts undergoing compression. Accurate characterization and modeling of the breast curvature and shape was achieved and will be used for various image processing and clinical tasks.
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影响因子：
3.5
作者：
DANCE, DR
通讯作者：
DANCE, DR
影响因子：
3.8
作者：
Feng, Steve Si Jia;Patel, Bhavika;Sechopoulos, Ioannis
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3.8
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3.8
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