Intermittent "real-time" fMRI feedback is superior to continuous presentation for a motor imagery task: a pilot study.
Intermittent "real-time" fMRI feedback is superior to continuous presentation for a motor imagery task: a pilot study.
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DOI：
10.1111/j.1552-6569.2010.00529.x
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发表时间：
2012-01
期刊：
影响因子：
--
通讯作者：
George MS
中科院分区：
文献类型：
--
作者：
Johnson KA;Hartwell K;LeMatty T;Borckardt J;Morgan PS;Govindarajan K;Brady K;George MS
实时功能磁共振成像反馈 (RTfMRIf) 是一项正在发展的技术，其方法学问题尚未得到解答。鉴于神经活动和可测量的血流动力学反应之间存在数秒的延迟，一个问题是向受试者呈现神经反馈的最佳方法。这项初步研究的主要目的是比较针对目标大脑活动的神经反馈的连续和间歇呈现方法。 13 名参与者执行了运动想象任务，并被指示使用 RTfMRIf 增加左前运动皮层单独定义区域的激活。比较具有连续或间歇反馈呈现的扫描的真实反馈和错误反馈之间的功能磁共振成像信号变化。更多的人能够通过间歇性反馈增加他们的功能磁共振成像信号，而一些人通过连续反馈减少信号。对反馈的评估本身会激活大量的大脑区域，而错误的反馈会导致大脑激活单独定义的感兴趣区域之外。正如本研究所实施的，间歇性反馈比连续反馈更能有效促进大脑活动的自我调节。此外，评估反馈的过程似乎涉及许多大脑区域，并且可以使用间歇性呈现来隔离这些区域。
Real-time fMRI feedback (RTfMRIf) is a developing technique, with unanswered methodological questions. Given a delay of seconds between neural activity and the measurable hemodynamic response, one issue is the optimal method for presentation of neurofeedback to subjects. The primary objective of this preliminary study was to compare the methods of continuous and intermittent presentation of neural feedback on targeted brain activity. Thirteen participants performed a motor imagery task and were instructed to increase activation in an individually defined region of left premotor cortex using RTfMRIf. The fMRI signal change was compared between real and false feedback for scans with either continuous or intermittent feedback presentation. More individuals were able to increase their fMRI signal with intermittent feedback, while some individuals had decreased signal with continuous feedback. The evaluation of feedback itself activated an extensive amount of brain regions, and false feedback resulted in brain activation outside of the individually defined region of interest. As implemented in this study, intermittent presentation of feedback is more effective than continuous presentation in promoting self-modulation of brain activity. Furthermore, it appears that the processes of evaluating feedback involve many brain regions and that can be isolated using intermittent presentation.
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DOI：
10.1073/pnas.0505210102
发表时间：
2005-12-20
影响因子：
11.1
作者：
deCharms, RC;Maeda, F;Mackey, SC
通讯作者：
Mackey, SC
影响因子：
1.7
作者：
Yoo, Seung-Schik;O'Leary, Heather M.;Jolesz, Ferenc A.
通讯作者：
Jolesz, Ferenc A.
影响因子：
5.7
作者：
Voyvodic, JT
通讯作者：
Voyvodic, JT
DOI：
10.2463/mrms.5.157
发表时间：
2006-10-01
期刊：
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
影响因子：
--
作者：
Bagarinao, Epifanio;Nakai, Toshiharu;Tanaka, Yoshio
通讯作者：
Tanaka, Yoshio
影响因子：
5.7
作者：
DeCharms, RC;Christoff, K;Gabrieli, JDE
通讯作者：
Gabrieli, JDE