Analysis of synaptic potentials in mitral cells in the isolated turtle olfactory bulb.
Analysis of synaptic potentials in mitral cells in the isolated turtle olfactory bulb.
复制标题
离体龟嗅球二尖瓣细胞突触电位的分析。
DOI：
10.1113/jphysiol.1981.sp013708
复制
发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Shepherd,GM
中科院分区：
文献类型：
--
作者：
Mori,K;Nowycky,MC;Shepherd,GM
1. The synaptic responses of mitral cells have been analysed in intracellular recordings from the isolated olfactory bulb of the turtle. 2. The response of a mitral cell to a single volley in the lateral olfactory tract consisted of and antidromic impulse and a complex hyperpolarizing potential that had the properties of an inhibitory post‐synaptic potential. The inhibitory response consisted of two successive components I1 and I2, followed by a prolonged hyperpolarization. 3. High‐gain recordings revealed miniature hyperpolarizing potentials during the I1 and I2 responses. Both the miniature potentials and the I1 and I2 responses were increased in amplitude by depolarizing injected currents, and decreased and reversed in polarity by hyperpolarizing currents. The input conductance was increased during the I2 component. In some cells the I1 and I2 components, recorded with micropipettes filled with potassium acetate or potassium citrate, were depolarizing. 4 A single orthodromic volley in the olfactory nerves elicited a complex depolarizing‐hyperpolarizing potential in mitral cells. The depolarization consisted of two successive components, E1 and E2. The hyperpolarization consisted of two successive components, I1 and I2, followed by a prolonged hyperpolarization. 5. The depolarizing components had the properties of excitatory post‐synaptic potentials. They decreased in amplitude with depolarizing current injection and increased with hyperpolarizing injection. The hyperpolarizing components resembled the I1 and I2 components of the tract‐evoked responses in their timing and properties. 6. It is postulated that the E1 component reflects the initial excitation by olfactory nerve terminals of the mitral cell dendritic tufts in the olfactory glomeruli. The I1 component is postulated to arise from dendrodendritic synaptic input mediated by interneurones, mainly granule cells. The E2 and I2 components are likely to arise mainly from intrinsic synaptic circuits within the olfactory bulb.
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兔子前连合齐射对嗅球神经元的激活和抑制。
DOI：
10.1113/jphysiol.1978.sp012363
发表时间：
1978
期刊：
The Journal of Physiology
影响因子：
--
作者：
K. Mori;S. Takagi
通讯作者：
S. Takagi
影响因子：
2.9
作者：
H. Mclennan
通讯作者：
H. Mclennan
GABA 作为嗅球颗粒细胞抑制递质的药理学证据。
影响因子：
2.9
作者：
R. Nicoll
通讯作者：
R. Nicoll
突触抑制的阻断揭示了离体龟嗅球中持久的突触兴奋。
影响因子：
2.5
作者：
Nowycky,MC;Mori,K;Shepherd,GM
通讯作者：
Shepherd,GM
兔嗅球二尖瓣细胞树突状抑制突触的细胞内研究。
DOI：
--
发表时间：
1978
期刊：
Journal of Physiology
影响因子：
--
作者：
K. Mori;S. Takagi
通讯作者：
S. Takagi