Clinical application of contrast enhanced ultrasound to diagnose benign prostatic hyperplasia.
Clinical application of contrast enhanced ultrasound to diagnose benign prostatic hyperplasia.
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DOI：
10.1186/1746-1596-9-133
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发表时间：
2014-07-01
影响因子：
2.6
通讯作者：
Gao W
中科院分区：
文献类型：
--
作者：
Shi J;Yin X;Xu R;Wang Y;Jin L;Gao W
本研究旨在通过对比造影增强超声（CEUS）在良性前列腺增生（BPH）与正常人的造影参数，探讨超声造影（CEUS）在诊断BPH中的临床意义。对60例前列腺增生患者（73.5±20.5岁）和30例接受超声造影检查的无前列腺疾病的正常对照（75.3±19.7岁）进行回顾性研究。在感兴趣的区域获得所有试验的时间-强度曲线。采用ACQ软件对图像进行处理，得到图像到达时间（AT）、峰值强度(P)、到达峰值时间（TP）、曲线下面积（AUC）、平均穿越时间（MTT）和消光时间（ET）。评价前列腺增生与正常组织前列腺内外腺的差异。前列腺增生的内外腺界限清晰。BPH外腺AT、TP、MTT、ET、P显著高于对照组。内腺MTT、ET、AUC和P均显著高于对照组。超声造影诊断BPH的准确率为95.6%，敏感性和特异性分别为95.0%和96.7%。在这些显著变化的参数中，内腺的MTT、ET和AUC以及外腺的AT、TP的增加最有可能与BPH有关。这些参数为BPH的诊断提供了客观的视觉评价。本文的虚拟幻灯片可以在这里找到：http://www.diagnosticpathology.diagnomx.eu/vs/4852383312229155
This study aimed to investigate the clinical significance of contrast enhanced ultrasound (CEUS) in diagnosis of benign prostatic hyperplasia (BPH) through comparing CEUS parameters between BPH and normal person. A retrospective study of sixty BPH patients (aged 73.5 ± 20.5 years old) and thirty normal controls without prostate diseases (aged 75.3 ± 19.7 years old) who had accepted CEUS detection were performed. Time-intensity curves were obtained for all tests in regions of interest. Images were processed using ACQ software and the following parameters were obtained: arrival time (AT), peak intensity (P), time to peak (TP), area under the curve (AUC), mean transit time (MTT) and extinction time (ET). Differences in inner and outer gland of prostate between BPH and the normal tissue were evaluated. There was a clear boundary between the inner and outer gland of BPH prostate. AT, TP, MTT, ET and P in BPH outer gland were significantly higher than the control group. In inner gland, MTT, ET, AUC and P were also significantly higher than the controls. The accurate rate to diagnose BPH using CEUS was 95.6%, and the sensitivity and specificity were 95.0% and 96.7%, respectively. Among these significantly changed parameters, the increases of MTT, ET and AUC in inner gland and AT, TP in outer gland were most likely related to BPH. These parameters provide an objective visual assessment to diagnosis of BPH. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/4852383312229155
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影响因子：
2.6
作者：
Tian Y;Zhao L;Zhang H;Liu X;Zhao L;Zhao X;Li Y;Li J
通讯作者：
Li J
DOI：
10.2214/ajr.10.6330
发表时间：
2011-10
期刊：
AJR. American journal of roentgenology
影响因子：
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通讯作者：
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影响因子：
2.6
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Imai, Yasuharu