Phyto-mediated metallic nano-architectures via Melissa officinalis L.: synthesis, characterization and biological properties.
Phyto-mediated metallic nano-architectures via Melissa officinalis L.: synthesis, characterization and biological properties.
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DOI：
10.1038/s41598-017-12804-7
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发表时间：
2017-09-29
影响因子：
4.6
通讯作者：
Ditu LM
中科院分区：
文献类型：
--
作者：
Fierascu I;Georgiev MI;Ortan A;Fierascu RC;Avramescu SM;Ionescu D;Sutan A;Brinzan A;Ditu LM
基于绿色化学原理，开发获得具有抗微生物性能的新材料的方法已经成为过去几年的研究目标。本论文描述了以香蜂草乙醇提取物为载体，通过植物介导合成金属纳米结构（金和银）。（通过加速溶剂萃取获得）。不同的分析方法被应用于提取物成分的评价，以及植物合成材料的表征。采用洋葱法对合成材料的细胞遗传毒性进行了评价，同时采用定性和定量方法对合成材料的抗菌活性进行了研究。结果表明，银纳米颗粒（平均直径13 nm）和金纳米颗粒（直径约10 nm）的合成是成功的。10 nm）;双金属纳米颗粒被证明具有核壳花状结构，由较小的颗粒（约10 nm）组成。8nm）。银纳米颗粒对核DNA损伤无明显作用。Au纳米颗粒表现出核保护作用，但在A.洋葱根分生组织细胞。抗微生物测定的结果显示，银纳米颗粒对大多数测试菌株具有活性，因为对B获得最低MIC值。cereus（近似）0.0015 mM）。
The development of methods for obtaining new materials with antimicrobial properties, based on green chemistry principles has been a target of research over the past few years. The present paper describes the phyto-mediated synthesis of metallic nano-architectures (gold and silver) via an ethanolic extract of Melissa officinalis L. (obtained by accelerated solvent extraction). Different analytic methods were applied for the evaluation of the extract composition, as well as for the characterization of the phyto-synthesized materials. The cytogenotoxicity of the synthesized materials was evaluated by Allium cepa assay, while the antimicrobial activity was examined by applying both qualitative and quantitative methods. The results demonstrate the synthesis of silver nanoparticles (average diameter 13 nm) and gold nanoparticles (diameter of ca. 10 nm); the bi-metallic nanoparticles proved to have a core-shell flower-like structure, composed of smaller particles (ca. 8 nm). The Ag nanoparticles were found not active on nuclear DNA damage. The Au nanoparticles appeared nucleoprotective, but were aggressive in generating clastogenic aberrations in A. cepa root meristematic cells. Results of the antimicrobial assays show that silver nanoparticles were active against most of the tested strains, as the lowest MIC value being obtained against B. cereus (approx. 0.0015 mM).
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影响因子：
4.6
作者：
Goudarzi M;Mir N;Mousavi-Kamazani M;Bagheri S;Salavati-Niasari M
通讯作者：
Salavati-Niasari M
影响因子：
3.1
作者：
Ammons MC;Ward LS;James GA
通讯作者：
James GA
影响因子：
5.8
作者：
Kalishwaralal, Kalimuthu;BarathManiKanth, Selvaraj;Gurunathan, Sangiliyandi
通讯作者：
Gurunathan, Sangiliyandi
影响因子：
6
作者：
Dastmalchi, Keyvan;Dorman, H. T. Damien;Hiltunen, Raimo
通讯作者：
Hiltunen, Raimo
影响因子：
2.1
作者：
Firbas, Peter;Amon, Tomaz
通讯作者：
Amon, Tomaz