Negative affect, affect-related impulsivity, and receptive syringe sharing among people who inject drugs.
Negative affect, affect-related impulsivity, and receptive syringe sharing among people who inject drugs.
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DOI：
10.1037/adb0000590
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发表时间：
2020-11
期刊：
影响因子：
--
通讯作者：
Donenberg G
中科院分区：
文献类型：
--
作者：
Mackesy-Amiti ME;Boodram B;Donenberg G
注射吸毒者（PWID）之间的接受性注射器共享（RSS）是丙型肝炎病毒和艾滋病毒感染的风险因素。患有边缘性人格障碍（BPD）的PWID会增加RSS的风险，但目前尚不清楚是什么导致了这种关联。本研究使用生态瞬时评估（EMA）来研究与BPD相关的特征，以及PWID中的RSS。我们通过美国伊利诺斯州芝加哥的两个社区外展干预项目注射器服务项目地点招募了18-35岁的PWID。在基线访谈后，参与者使用移动的手机应用程序对为期两周的情绪、物质使用和注射风险行为的瞬时调查做出回应。对于每一个瞬间的评估，负面情绪描述符的评级相结合，以创建总的负面影响（NA）的措施，和NA组件的沮丧，羞耻，愤怒，易怒，和担心。RSS的定义是参与者的反应，表明他们使用了别人使用过的注射器。我们估计混合效应逻辑模型，回归RSS基线影响相关的冲动，滞后瞬时NA，和相互作用项。在完成至少两次EMA评估的163名参与者中，152名（93%）报告了至少一次注射事件，并且需要将有效的注射前情绪评估纳入分析。我们发现，与情感相关的冲动，加上注射前几个小时的焦虑情绪，预测RSS的风险增加。PWID在情绪调节方面有困难，在焦虑或紧张期间可能会增加RSS的风险。
Receptive syringe sharing (RSS) among people who inject drugs (PWID) is a risk factor for hepatitis C virus and HIV infections. PWID with borderline personality disorder (BPD) have increased risk of RSS, but it remains unclear what drives this association. This study used ecological momentary assessment (EMA) to study characteristics associated with BPD, and RSS among PWID. We recruited PWID, age 18-35, through two Community Outreach Intervention Projects syringe service program sites in Chicago, Illinois, USA. After a baseline interview, participants used a mobile phone app to respond to momentary surveys on mood, substance use, and injection risk behavior for two weeks. For each momentary assessment, ratings on negative mood descriptors were combined to create measures of total negative affect (NA), and NA components of dejection, shame, anger, irritability, and worry. RSS was defined by participant responses indicating that they had used a syringe that someone else had used. We estimated mixed effects logistic models, regressing RSS on baseline affect-related impulsivity, lagged momentary NA, and the interaction term. Out of 163 participants who completed at least two EMA assessments, 152 (93%) reported at least one injection event and had valid pre-injection mood assessments required to be included in the analysis. We found that affect-related impulsivity, combined with worried mood in the hours preceding the injection episode, predicted increased risk of RSS. PWID having difficulties with emotion regulation may be at increased risk of RSS during periods of anxiety or tension.
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