Gender differences in the associations among marijuana use, cigarette use, and symptoms of depression during adolescence and young adulthood.

Gender differences in the associations among marijuana use, cigarette use, and symptoms of depression during adolescence and young adulthood.
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DOI:
10.1016/j.addbeh.2015.05.014
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发表时间:
2015-10
影响因子:
4.4
通讯作者:
Mermelstein, Robin J.
Mermelstein, Robin J.
中科院分区:
医学2区
文献类型:
--
作者:
Crane, Natania A.;Langenecker, Scott A.;Mermelstein, Robin J.

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随着大麻使用量的增加,我们有必要更好地了解性别、吸烟和抑郁等因素与青春期和成年早期吸食大麻的关系。我们对进入青年期的青少年进行了为期六年的纵向研究,考察了这些变量之间的纵向关系。1263人参与了这项研究。参与者在15-16岁时被抽样调查是否吸烟。在基线、6个月、15个月、24个月、60个月和72个月时评估吸烟和使用大麻的频率以及抑郁症状。香烟使用频率和抑郁症状与大麻使用频率相关(p值< 0.001),特别是在青少年中,但这些关系存在重要的性别差异。具体来说,男性的抑郁症状与大麻使用频率有关(p< 0.001),而女性则无关(p= 0.62)。此外,大麻使用频率与香烟使用频率增加有关,特别是在有较高抑郁症状的男性中(p< 0.001)。然而,这种影响在女性中没有发现。探索性分析表明,使用频率和抑郁之间的关系是大麻特有的,而不是香烟。在男性中,大麻的使用与抑郁症状和吸烟频率密切相关,表明这些有害因素在男性中汇合,而在女性中则不然。与大麻使用有关的因素的性别差异可能意味着使用大麻的风险和后果不同,并对预防和干预工作产生影响。
As prevalence of marijuana use increases, it is important that we better understand how factors like gender, cigarette use, and depression are related to marijuana use during adolescence and young adulthood. We examined longitudinal relationships among these variables in adolescents moving into young adulthood who were studied longitudinally for six years. 1,263 individuals were included in the study. Participants were oversampled for ever-smoking a cigarette at baseline, when they were 15-16 years old. Frequency of cigarette smoking and marijuana use, as well as depression symptoms were assessed at baseline, 6, 15-, 24-, 60- and 72- months. Cigarette use frequency and depression symptoms were associated with frequency of marijuana use (p-values <.001), particularly in adolescence, but there were important gender differences in these relationships. Specifically, symptoms of depression were related to marijuana use frequency among males (p<.001), but not females (p=.62). In addition, frequency of marijuana use was associated with increased cigarette use frequency, especially among males who had higher symptoms of depression (p<.001). However, this effect was not seen among females. Exploratory analyses suggested relationships between frequency of use and depression are specific to marijuana, not cigarettes. Marijuana use is strongly related to depression symptoms and cigarette use frequency in males, indicating that in males these detrimental factors converge, whereas in females they do not. Gender differences in the factors related to marijuana use may mean that there are different risks for and consequences from use and have implications for prevention and intervention efforts.
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