Recurrent falls in Parkinson's disease: a systematic review.

Recurrent falls in Parkinson's disease: a systematic review.
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DOI:
10.1155/2013/906274
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发表时间:
2013
期刊:
Parkinson's disease
影响因子:
--
通讯作者:
Canning CG
Canning CG
中科院分区:
其他
文献类型:
--
作者:
Allen NE;Schwarzel AK;Canning CG

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大多数帕金森氏症(PD)患者会跌倒,许多人会反复跌倒。本综述的目的是检查复发性跌倒的范围,并确定与复发性跌倒相关的因素。在数据库中搜索了关于PD患者复发性跌倒的前瞻性报告的期刊文章,确定了22项研究。在这些研究中,60.5%(35%至90%)的参与者报告至少有一次跌倒,39%(18%至65%)的参与者报告反复跌倒。经常跌倒者平均每人每年跌倒4.7至67.6次(整体平均跌倒20.8次)。与复发性跌倒相关的因素包括:积极的跌倒史、疾病严重程度和持续时间增加、运动障碍增加、多巴胺激动剂治疗、左旋多巴剂量增加、认知障碍、害怕跌倒、步态冻结、行动能力受损和体力活动减少。PD患者复发性跌倒的频率范围很广,这表明根据跌倒频率将复发性跌倒者分类为亚组是有益的。鉴于有几个因素与复发性跌倒特别相关,需要紧急评估专门针对复发性跌倒的跌倒管理和预防策略,以便为临床实践提供信息。
Most people with Parkinson's disease (PD) fall and many experience recurrent falls. The aim of this review was to examine the scope of recurrent falls and to identify factors associated with recurrent fallers. A database search for journal articles which reported prospectively collected information concerning recurrent falls in people with PD identified 22 studies. In these studies, 60.5% (range 35 to 90%) of participants reported at least one fall, with 39% (range 18 to 65%) reporting recurrent falls. Recurrent fallers reported an average of 4.7 to 67.6 falls per person per year (overall average 20.8 falls). Factors associated with recurrent falls include: a positive fall history, increased disease severity and duration, increased motor impairment, treatment with dopamine agonists, increased levodopa dosage, cognitive impairment, fear of falling, freezing of gait, impaired mobility and reduced physical activity. The wide range in the frequency of recurrent falls experienced by people with PD suggests that it would be beneficial to classify recurrent fallers into sub-groups based on fall frequency. Given that there are several factors particularly associated with recurrent falls, fall management and prevention strategies specifically targeting recurrent fallers require urgent evaluation in order to inform clinical practice.
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