Autistic empathy toward autistic others.
Autistic empathy toward autistic others.
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DOI：
10.1093/scan/nsu126
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发表时间：
2015-02
影响因子：
4.2
通讯作者：
Okazawa H
中科院分区：
文献类型：
--
作者：
Komeda H;Kosaka H;Saito DN;Mano Y;Jung M;Fujii T;Yanaka HT;Munesue T;Ishitobi M;Sato M;Okazawa H
自闭症谱系障碍（ASD）患者被认为缺乏自我意识，难以与他人共情。虽然这些缺陷已经在以前的研究中得到证实，但大多数目标刺激是为典型发育个体构建的。我们在患有和不患有ASD的个体中采用了能够索引自我相关加工的判断任务。14名患有高功能ASD的日本男性和1名日本女性（17-41岁），13名日本男性和2名日本女性（22-40岁），他们的年龄、完整智商和言语智商得分都与ASD参与者相匹配。结果表明，自闭症个体的腹内侧前额叶皮层在自闭症特征的反应中显著激活，而TD个体在非自闭症特征的反应中显著激活。虽然在TD个体中，腹内侧前额叶皮层和颞上回之间的额-后网络参与了非自闭症特征的加工，但在ASD个体中，另一个网络参与了自闭症特征的加工。这表明自闭症谱系障碍患者对其他自闭症谱系障碍患者有一种非典型的共情形式。
Individuals with autism spectrum disorder (ASD) are thought to lack self-awareness and to experience difficulty empathizing with others. Although these deficits have been demonstrated in previous studies, most of the target stimuli were constructed for typically developing (TD) individuals. We employed judgment tasks capable of indexing self-relevant processing in individuals with and without ASD. Fourteen Japanese men and 1 Japanese women with high-functioning ASD (17–41 years of age) and 13 Japanese men and 2 TD Japanese women (22–40 years of age), all of whom were matched for age and full and verbal intelligence quotient scores with the ASD participants, were enrolled in this study. The results demonstrated that the ventromedial prefrontal cortex was significantly activated in individuals with ASD in response to autistic characters and in TD individuals in response to non-autistic characters. Although the frontal–posterior network between the ventromedial prefrontal cortex and superior temporal gyrus participated in the processing of non-autistic characters in TD individuals, an alternative network was involved when individuals with ASD processed autistic characters. This suggests an atypical form of empathy in individuals with ASD toward others with ASD.
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影响因子：
10.6
作者：
Constantino, JN;Todd, RD
通讯作者：
Todd, RD
影响因子：
14.5
作者：
Just, MA;Cherkassky, VL;Minshew, NJ
通讯作者：
Minshew, NJ
影响因子：
5.7
作者：
Friston, KJ;Zarahn, E;Dale, AM
通讯作者：
Dale, AM
影响因子：
3.3
作者：
Bruck, Maggie;London, Kamala;Goodman, June
通讯作者：
Goodman, June
DOI：
10.1111/j.1471-3802.2010.01147.x
发表时间：
2010-06-01
影响因子：
1.5
作者：
Asberg, Jakob;Sandberg, Annika Dahlgren
通讯作者：
Sandberg, Annika Dahlgren