Attainment and loss of early social-communication skills across neurodevelopmental conditions in the Norwegian Mother, Father and Child Cohort Study.
Attainment and loss of early social-communication skills across neurodevelopmental conditions in the Norwegian Mother, Father and Child Cohort Study.
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挪威母亲、父亲和儿童队列研究中神经发育状况下早期社交沟通技能的获得和丧失。
DOI：
10.1111/jcpp.13792
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发表时间：
2024
期刊：
影响因子：
--
通讯作者：
Thurm,Audrey
中科院分区：
文献类型：
--
作者：
Havdahl,Alexandra;Farmer,Cristan;Surén,Pål;Øyen,Anne-Siri;Magnus,Per;Susser,Ezra;Lipkin,WIan;Reichborn-Kjennerud,Ted;Stoltenberg,Camilla;Bishop,Somer;Thurm,Audrey
背景延迟和早期出现的社会沟通技能的丧失通常被认为是自闭症所独有的。然而，大多数回归研究依赖于回顾性回忆和临床样本。在这里，我们研究的实现和损失的社会沟通技能在人口为基础的挪威母亲，父亲和儿童队列研究（MoBa）。方法母亲们评价他们的孩子的实现10个早期出现的社会沟通技能在18岁和36个月（N = 40，613，50.9%男性）。据报告，18个月时丧失技能，但36个月时丧失技能。在36个月时，母亲还回忆了孩子是否失去了社交能力。挪威患者登记处被用来捕捉诊断自闭症谱系障碍（自闭症）和其他神经发育障碍（NDDs）。结果延迟在至少一个技能中观察到14%的样本和损失在5.4%。回忆社交沟通技能丧失的情况罕见（0.86%），与前瞻性报告的丧失的收敛性较低。延迟，尤其是损失与自闭症诊断（n = 383）与无自闭症诊断（n = 40，230; ≥ 3项技能延迟：OR = 7.09 [4.15，12.11]; ≥ 3项技能损失：OR = 30.66 [17.30，54.33]）的几率增加相关。与其他一些NDD相比，它们也与自闭症的可能性增加有关。延迟（相对风险[RR]= 4.16 [2.08，8.33]）和损失（RR = 10.00 [3.70，25.00]）与自闭症与ADHD的可能性增加相关，（RR = 4.35 [1.28，14.29]），但不延迟（RR = 2.00 [0.78，5.26]），与语言障碍相比，自闭症的可能性增加。相反，相对于智力残疾，（RR = 0.11 [0.06，0.21]），丧失与自闭症与智力残疾的可能性没有可靠的相关性（RR = 1.89 [0.44，8.33]）结论这项基于人群的研究表明，早期社会沟通技能的丧失比使用回顾性报告的研究更常见，在几种NDD诊断中观察到（不仅仅是自闭症）。然而，大多数NDD诊断的儿童在这些前瞻性测量的技能中没有表现出延迟或丧失。
BackgroundDelays and loss of early‐emerging social‐communication skills are often discussed as unique to autism. However, most studies of regression have relied on retrospective recall and clinical samples. Here, we examine attainment and loss of social‐communication skills in the population‐based Norwegian Mother, Father and Child Cohort Study (MoBa).MethodsMothers rated their child's attainment of 10 early‐emerging social‐communication skills at ages 18 and 36 months (N= 40,613, 50.9% male). Prospectively reported loss was defined as skill presence at 18 months but absence at 36 months. At 36 months, mothers also recalled whether the child had lost social‐communication skills. The Norwegian Patient Registry was used to capture diagnoses of Autism Spectrum Disorder (autism) and other neurodevelopmental disabilities (NDDs).ResultsDelay in at least one skill was observed in 14% of the sample and loss in 5.4%. Recalled loss of social‐communication skills was rare (0.86%) and showed low convergence with prospectively reported loss. Delay and especially loss were associated with elevated odds of an autism diagnosis (n= 383) versus no autism diagnosis (n= 40,230; ≥3 skills delayed: OR = 7.09[4.15,12.11]; ≥3 skills lost: OR = 30.66[17.30,54.33]). They were also associated with an increased likelihood of autism compared to some other NDDs. Delay (relative risk [RR] = 4.16[2.08, 8.33]) and loss (RR = 10.00[3.70, 25.00]) associated with increased likelihood of autism versus ADHD, and loss (RR = 4.35[1.28,14.29]), but not delay (RR = 2.00[0.78,5.26]), associated with increased likelihood of autism compared to language disability. Conversely, delay conferred decreased likelihood of autism versus intellectual disability (RR = 0.11[0.06,0.21]), and loss was not reliably associated with likelihood of autism versus intellectual disability (RR = 1.89[0.44,8.33]).ConclusionsThis population‐based study suggests that loss of early social communication skills is more common than studies using retrospective reports have indicated and is observed across several NDD diagnoses (not just autism). Nevertheless, most children with NDD diagnoses showed no reported delay or loss in these prospectively measured skills.
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DOI：
10.1002/aur.1903
发表时间：
2018-03
期刊：
Autism research : official journal of the International Society for Autism Research
影响因子：
--
作者：
Thurm A;Powell EM;Neul JL;Wagner A;Zwaigenbaum L
通讯作者：
Zwaigenbaum L
童年时期的语言退化。
影响因子：
3.8
作者：
S. Shinnar;I. Rapin;S. Arnold;R. Tuchman;L. Shulman;K. Ballaban;M. Maw;R. Deuel;Fred R. Volkmar
通讯作者：
Fred R. Volkmar
确定 1-6 岁幼儿语言发展的里程碑。
影响因子：
3.1
作者：
Margot I. Visser;S. Reijneveld;W. Krijnen;C. P. van der Schans;Margreet R. Luinge
通讯作者：
Margreet R. Luinge
影响因子：
1.5
作者：
Luyster, R;Richler, J;Lord, C
通讯作者：
Lord, C
影响因子：
3.9
作者：
Baird, Gillian;Charman, Tony;Simonoff, Emily
通讯作者：
Simonoff, Emily