The dual role of bacteriocins as anti- and probiotics.
The dual role of bacteriocins as anti- and probiotics.
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DOI：
10.1007/s00253-008-1726-5
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发表时间：
2008-12
影响因子：
5
通讯作者：
Riley MA
中科院分区：
文献类型：
--
作者：
Gillor O;Etzion A;Riley MA
益生菌应用中使用的细菌有助于维持或恢复宿主的天然微生物菌群。益生菌成功地胜过不希望的物种的能力通常是由于产生有效的抗微生物毒素，或者通过产生有效的抗微生物毒素而增强。其中最常见的是细菌素，这是一个在所有主要细菌谱系中发现的功能多样的大型抗菌剂家族。最近的研究表明，这些蛋白质毒素在介导细菌菌株和密切相关的物种之间的竞争动力学中起着关键作用。细菌素生产菌株作为益生菌和生物保护剂的潜在用途最近受到越来越多的关注。本次综述将报告最近涉及使用此类菌株的努力，特别关注用于人类、牲畜和水产养殖的新兴益生菌疗法。
Bacteria employed in probiotic applications help to maintain or restore a host's natural microbial floral. The ability of probiotic bacteria to successfully outcompete undesired species is often due to, or enhanced by, the production of potent antimicrobial toxins. The most commonly encountered of these are bacteriocins, a large and functionally diverse family of antimicrobials found in all major lineages of Bacteria. Recent studies reveal that these proteinaceous toxins play a critical role in mediating competitive dynamics between bacterial strains and closely related species. The potential use of bacteriocin-producing strains as probiotic and bioprotective agents has recently received increased attention. This review will report on recent efforts involving the use of such strains, with a particular focus on emerging probiotic therapies for humans, livestock, and aquaculture.
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影响因子：
4.4
作者：
Barrett, Eoin;Hayes, Maria;Hill, Colin
通讯作者：
Hill, Colin
影响因子：
4
作者：
Choi, HJ;Lee, HS;Yoon, SS
通讯作者：
Yoon, SS
DOI：
10.1046/j.1365-2621.1998.3320139.x
发表时间：
1998-04-01
影响因子：
3.3
作者：
Alderman, DJ;Hastings, TS
通讯作者：
Hastings, TS
DOI：
10.1073/pnas.78.10.6324
发表时间：
1981-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
CHAO, L;LEVIN, BR
通讯作者：
LEVIN, BR
DOI：
10.1155/s1064744901000060
发表时间：
2001-01-01
影响因子：
--
作者：
Aroutcheva, A A;Simoes, J A;Faro, S
通讯作者：
Faro, S