Evidence that a phage T4 DNA packaging enzyme is a processed form of the major capsid gene product.
Evidence that a phage T4 DNA packaging enzyme is a processed form of the major capsid gene product.
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有证据表明噬菌体 T4 DNA 包装酶是主要衣壳基因产物的加工形式。
DOI:
10.1016/0092-8674(85)90293-4
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发表时间:
1985
期刊:
影响因子:
64.5
通讯作者:
Black,LW
中科院分区:
文献类型:
--
作者:
Rao,VB;Black,LW
A phage T4 DNA packaging enzyme appears to arise as a processed form of the major T4 capsid structural protein gp23. The enzyme activity and antigen are missing from all head gene mutants that block the morphogenetic proteolytic processing reactions of the head proteins in vivo. The enzyme antigen can be formed in vitro by T4 (gp21) specific processing of gp23 containing extracts. Enzyme antigen is found in active processed proheads but not in full heads. The enzyme and the major capsid protein show immunological cross-reactivity, produce common peptides upon proteolysis, and share an assembly-conformation-dependent ATP binding site. The packaging enzyme and the mature capsid protein (gp23’) both appear to arise from processing of gp23, the former as a minor product of a specific gp23 structure in the prohead, acting in DNA packaging as a DNA-dependent ATPase, and a headful-dependent terminase.
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影响因子:
2.7
作者:
E. Bandman;R. Matsuda;R. Strohman
通讯作者:
R. Strohman
DOI:
10.1038/newbio241017a0
发表时间:
1973
期刊:
Nature: New biology
影响因子:
--
作者:
F. Streter;J. Gergely;S. Salmons;S. Salmons;F. Romanul
通讯作者:
F. Romanul
影响因子:
2.4
作者:
By R. B. Muir;A. H. Al;David Allbrook;Departmtient
通讯作者:
Departmtient
影响因子:
56.9
作者:
L. Leinwand;R. Fournier;B. Nadal-Ginard;T. Shows
通讯作者:
L. Leinwand;R. Fournier;B. Nadal-Ginard;T. Shows
影响因子:
3.5
作者:
K. Seedorf;U. Seedorf;D. Pette
通讯作者:
D. Pette