Changes in optic disk characteristics and number of nerve fibers in experimental glaucoma.
Changes in optic disk characteristics and number of nerve fibers in experimental glaucoma.
复制标题
实验性青光眼中视盘特征和神经纤维数量的变化。
DOI：
10.1016/s0002-9394(14)74482-4
复制
发表时间：
1992
影响因子：
4.2
通讯作者：
Pease,ME
中科院分区：
文献类型：
--
作者：
Varma,R;Quigley,HA;Pease,ME
我们比较了12只患有单侧实验性青光眼的食蟹猴的视神经纤维数量的变化，比较了视杯/视盘比率和神经视网膜边缘面积与视神经纤维数量的变化。根据在眼压升高前后获得的立体视盘照片，估计视杯/视盘比率和神经视网膜边缘面积与视盘面积的变化。青光眼患者神经中视神经纤维的数量变化是通过与他们的正常神经进行比较来估计的。视杯/视盘比率和神经视网膜边缘面积/视盘面积的变化与视神经纤维数量的估计变化之间存在显著的线性相关(r≥.85；P<；.0002)。在初始杯盘比为0.2~0.3和神经视网膜边缘面积与视盘面积之比为0.9的视盘中，视盘边缘面积与视盘面积之比增加0.1与视神经纤维损失分别为10%和9%有关。
We compared the change in cup/disk ratio and neuroretinal rim area-to-disk area to estimated change in the number of optic nerve fibers in 12 cynomolgus monkeys with unilateral experimental glaucoma. Changes in the cup/disk ratios and neuroretinal rim area-to-disk area were estimated from stereoscopic optic disk photographs that were obtained before and after the development of increased intraocular pressure. Change in the number of optic nerve fibers in the glaucomatous nerves was estimated by comparing them to their fellow normal nerves. A significant linear correlation was present between change in the cup/disk ratios and neuroretinal rim area-to-disk area, and estimated change in the number of optic nerve fibers (r≥ .85; P < .0002). In optic disks with initial cup/disk ratios of 0.2 to 0.3 and neuroretinal rim area-to-disk area of 0.9, an increase in the cup/disk ratio of 0.1 and a decrease of 0.1 in the neuroretinal rim area-to-disk area is associated with a 10% and 9% loss of optic nerve fibers, respectively.
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影响因子：
4.4
作者：
H. Quigley;Rosario Sanchez;G. Dunkelberger;N. L'Hernault;T. Baginski
通讯作者：
H. Quigley;Rosario Sanchez;G. Dunkelberger;N. L'Hernault;T. Baginski
影响因子：
3.7
作者：
通讯作者：
--
视盘和神经纤维层检查在监测早期青光眼损伤进展中的评估。
影响因子：
13.7
作者：
Quigley,HA;Katz,J;Derick,RJ;Gilbert,D;Sommer,A
通讯作者：
Sommer,A
通过电子显微镜研究恒河猴视神经乳头中轴突和神经胶质元件的分布。
DOI：
--
发表时间：
1976
期刊：
American journal of ophthalmology-glaucoma
影响因子：
--
作者：
D. Minckler;I. McLean;M. Tso
通讯作者：
M. Tso
影响因子：
4.4
作者：
Sanchez,RM;Dunkelberger,GR;Quigley,HA
通讯作者：
Quigley,HA