Influence of non-Newtonian properties of blood on the wall shear stress in human atherosclerotic right coronary arteries.
Influence of non-Newtonian properties of blood on the wall shear stress in human atherosclerotic right coronary arteries.
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DOI：
10.3970/mcb.2011.008.073
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发表时间：
2011-03
期刊：
影响因子：
--
通讯作者：
Tang D
中科院分区：
文献类型：
--
作者：
Liu B;Tang D
本工作的目的是研究血液的非牛顿性质对动脉粥样硬化冠状动脉壁切应力（WSS）的影响，使用牛顿和非牛顿模型。进行数值模拟，以检查如何的空间和时间WSS分布的狭窄的大小，血液粘度和流速的影响。计算结果表明，血液粘度特性有相当大的影响的WSS的大小，特别是在扰动流观察。WSS分布在时间和空间上都是高度不均匀的，特别是在狭窄区域。最大WSS发生在狭窄的近端侧，靠近无狭窄的弯曲动脉的外壁。在整个心动周期内，狭窄区域远端内壁附近的管腔区域经历了较低的WSS。在狭窄的大小，血液粘度和流速的因素中，狭窄的大小对WSS的空间和时间分布的定性和定量的影响最显着。
The objective of this work is to investigate the effect of non-Newtonian properties of blood on the wall shear stress (WSS) in atherosclerotic coronary arteries using both Newtonian and non-Newtonian models. Numerical simulations were performed to examine how the spatial and temporal WSS distributions are influenced by the stenosis size, blood viscosity, and flow rate. The computational results demonstrated that blood viscosity properties had considerable effect on the magnitude of the WSS, especially where disturbed flow was observed. The WSS distribution is highly non-uniform both temporally and spatially, especially in the stenotic region. The maximum WSS occurred at the proximal side of the stenosis, near the outer wall in the curved artery with no stenosis. The lumen area near the inner wall distal to the stenosis region experienced a lower WSS during the entire cardiac cycle. Among the factors of stenosis size, blood viscosity, and flow rate, the size of the stenosis has the most significant effect on the spatial and temporal WSS distributions qualitatively and quantitatively.
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