Old Dogs Learning New Tricks: Neuroplasticity Beyond the Juvenile Period.
Old Dogs Learning New Tricks: Neuroplasticity Beyond the Juvenile Period.
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DOI：
10.1016/j.dr.2011.07.008
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发表时间：
2011-12-01
影响因子：
6.6
通讯作者：
Erisir, Alev
中科院分区：
文献类型：
--
作者：
Lillard, Angeline S.;Erisir, Alev
20年前，心理学上流行的观点是，尽管学习和形成新记忆是终身的事情，但与这些事件相关的神经变化都在现有的受体中。人们认为，从突触到神经元，在生命早期的一段漫长的时期后，不会出现新的神经硬件。在过去的20年里，另一种观点取代了这一观点，表明尽管青少年时期特别适合神经可塑性适应，但在以后的生活中也存在硬的神经可塑性变化。我们回顾了从动物和人类模型中选择的证据，表明它如何反映神经可塑性的三个原则：1)早期和后期经验诱导的神经结构变化在程度上比在类型上不同；2)导致神经可塑性变化的经历类型随着年龄的增长而缩小；(3)不同发育阶段神经结构和神经环境的基本差异导致了神经回路对变化适应性的差异。
Twenty years ago, the prevalent view in psychology was that although learning and the formation of new memories are lifelong occurrences, the neural changes associated with these events were all in the existing receptors. No new neural hardware, from synapses to neurons, was thought to appear after a protracted period early in life. In the past 20 years, another view has supplanted this one, showing that although the juvenile period is especially suited to neuroplastic adaptation, there is hard neuroplastic change later in life as well. We review a selection of evidence for this view from both animal and human models, showing how it reflects three principles of neuroplasticity: 1) earlier and later experience-induced changes to neuroarchitecture differ in degree more so than in type; 2) the types of experiences that lead to neuroplastic change narrow with age; and 3) differences in the amenability of neural circuitry to change result from basic differences in neuroarchitecture and neuroenvironment in different phases of development.
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DOI：
10.1016/j.devbrainres.2004.03.021
发表时间：
2004-07-19
期刊：
DEVELOPMENTAL BRAIN RESEARCH
影响因子：
--
作者：
Bédard, A;Parent, A
通讯作者：
Parent, A
影响因子：
--
作者：
Bartzokis, G;Beckson, M;Mintz, J
通讯作者：
Mintz, J
影响因子：
5.3
作者：
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通讯作者：
May, Arne
影响因子：
5.5
作者：
BLISS, TVP;LOMO, T
通讯作者：
LOMO, T
DOI：
10.3758/bf03206911
发表时间：
1999-07-01
期刊：
PERCEPTION & PSYCHOPHYSICS
影响因子：
--
作者：
Bradlow, AR;Akahane-Yamada, R;Tohkura, Y
通讯作者：
Tohkura, Y