Metabolomics in archaeological science: A review of their advances and present requirements.
Metabolomics in archaeological science: A review of their advances and present requirements.
复制标题
DOI：
10.1126/sciadv.adh0485
复制
发表时间：
2023-08-11
期刊：
影响因子：
13.6
通讯作者：
Inskip, Sarah
中科院分区：
文献类型：
--
作者：
Badillo-Sanchez, Diego;Serrano Ruber, Maria;Davies-Barrett, Anna;Jones, Donald J. L.;Hansen, Martin;Inskip, Sarah
代谢组学，研究代谢物（<1500道尔顿的小分子），已被假定为一种潜在的工具，以类似于其他组学的方式探索过去，例如，基因组学或蛋白质组学。考古学家使用代谢组学方法已有十年左右的时间，主要应用于粘附在考古材料上的有机残留物。由于灵敏度，分辨率的进步，以及不同分析平台的可用性增加，再加上分析所需的低质量/体积，代谢组学现在正在成为考古部门更可行的选择。我们小组提出的其他方法显示了代谢组学的多功能性，它是利用人类骨考古学遗骸了解人类过去的知识来源。代谢组学在考古学中有巨大的潜力，但需要进一步努力将其定位为常规技术。考古学家已经应用了代谢组学，取得了重要进展，但在实施过程中仍然存在困难。
Metabolomics, the study of metabolites (small molecules of <1500 daltons), has been posited as a potential tool to explore the past in a comparable manner to other omics, e.g., genomics or proteomics. Archaeologists have used metabolomic approaches for a decade or so, mainly applied to organic residues adhering to archaeological materials. Because of advances in sensitivity, resolution, and the increased availability of different analytical platforms, combined with the low mass/volume required for analysis, metabolomics is now becoming a more feasible choice in the archaeological sector. Additional approaches, as presented by our group, show the versatility of metabolomics as a source of knowledge about the human past when using human osteoarchaeological remains. There is tremendous potential for metabolomics within archaeology, but further efforts are required to position it as a routine technique. Archaeological scientists have applied metabolomics, producing key developments, but difficulties persist in its implementation.
登录
查看更多内容
骨研究中的代谢组学。
影响因子：
4.1
作者：
Fan J;Jahed V;Klavins K
通讯作者：
Klavins K
影响因子：
4.2
作者：
Brockbals, Lana;Habicht, Michael;Kraemer, Thomas
通讯作者：
Kraemer, Thomas
影响因子：
7.4
作者：
Decq, Louise;Abatih, Emmanuel;Lynen, Frederic
通讯作者：
Lynen, Frederic
影响因子：
2.8
作者：
Badillo-Sanchez, Diego;Ruber, Maria Serrano;Inskip, Sarah
通讯作者：
Inskip, Sarah
影响因子：
4.1
作者：
Creydt, Marina;Ludwig, Lea;Fischer, Markus
通讯作者：
Fischer, Markus