Daily life hour by hour, with and without cocaine: an ecological momentary assessment study.
Daily life hour by hour, with and without cocaine: an ecological momentary assessment study.
复制标题
DOI：
10.1007/s00213-010-1884-x
复制
发表时间：
2010-08
影响因子：
3.4
通讯作者：
Preston, Kenzie L.
中科院分区：
文献类型：
--
作者：
Epstein, David H.;Preston, Kenzie L.
如果不准确了解干预措施所叠加的基线行为，就无法理解干预措施的效果。对于非法药物滥用者来说，日常活动和情绪模式尚未以适合统计汇总的方式进行研究。比较可卡因依赖门诊患者在尿液验证的使用和戒断期间每小时的日常活动。在队列设计中，112 名服用美沙酮、滥用可卡因和海洛因的门诊患者志愿者样本在手持电脑上提供了 10,781 人日的生态瞬时评估 (EMA) 数据。使用 SAS Proc Glimmix（针对二元结果）和 Proc Mixed（针对连续结果），比较了 EMA 对有关当前位置、活动、同伴、情绪以及最近接触假定的药物使用触发因素的问题的回答在使用和戒断期间的情况进行比较。吸食可卡因的时间与下午无所事事、孤独、情绪消极有关，但出乎意料的是，它也与清晨或深夜工作的可能性更大有关。可卡因的全天伴随使用通常与先前对同一样本的分析中看到的急性使用前兆不同。禁欲期间负面情绪的一些指标有所增加。门诊患者使用和戒除可卡因数周与不同的情绪和行为模式有关；这里报告的详细的每小时数据应该有助于为旨在改变日常活动的治疗干预措施提供信息。研究结果还反驳了可卡因戒断症状从戒烟之日起单调减少的论点。
Effects of an intervention cannot be understood without precise knowledge of the baseline behavior on which the intervention is superimposed. For misusers of illicit drugs, patterns of daily activities and moods have not been studied in a way that is amenable to statistical aggregation. To compare hour-by-hour daily activities in cocaine-dependent outpatients during urine-verified periods of use and abstinence. In a cohort design, a volunteer sample of 112 methadone-maintained cocaine- and heroin-abusing outpatients provided ecological momentary assessment (EMA) data on handheld computers for 10,781 person-days. EMA responses to questions about current location, activities, companions, moods, and recent exposure to putative drug-use triggers were compared across periods of use and abstinence using SAS Proc Glimmix (for binary outcomes) and Proc Mixed (for continuous outcomes). Periods of cocaine use were associated with idle, solitary, affectively negative afternoons, but, unexpectedly, were also associated with a greater likelihood of early-morning or late-evening work. The whole-day concomitants of cocaine use were often distinct from the acute predecessors of use seen in prior analyses from the same sample. Several measures of negative mood increased during abstinence. Weeks of cocaine use and abstinence in outpatients are associated with distinct patterns of mood and behavior; the detailed hourly data reported here should help inform treatment interventions aimed at changing daily activities. The findings also argue against the contention that cocaine abstinence symptoms decrease monotonically from the day of cessation.
登录
查看更多内容
影响因子：
6
作者：
Foltin, RW;Fischman, MW
通讯作者：
Fischman, MW
影响因子：
4.2
作者：
Coffey, SF;Dansky, BS;Brady, KT
通讯作者：
Brady, KT
DOI：
10.1037/0022-006x.65.2.292.a
发表时间：
1997-04-01
影响因子：
5.9
作者：
Shiffman, S;Hufford, M;Kassel, JD
通讯作者：
Kassel, JD
影响因子：
4.4
作者：
Epstein, David H.;Marrone, Gina F.;Preston, Kenzie L.
通讯作者：
Preston, Kenzie L.
影响因子：
4.4
作者：
HEATHER, N;STALLARD, A;TEBBUTT, J
通讯作者：
TEBBUTT, J