Human Protein Reference Database--2009 update.
Human Protein Reference Database--2009 update.
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DOI：
10.1093/nar/gkn892
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发表时间：
2009-01
影响因子：
14.9
通讯作者：
Pandey A
中科院分区：
文献类型：
--
作者：
Keshava Prasad TS;Goel R;Kandasamy K;Keerthikumar S;Kumar S;Mathivanan S;Telikicherla D;Raju R;Shafreen B;Venugopal A;Balakrishnan L;Marimuthu A;Banerjee S;Somanathan DS;Sebastian A;Rani S;Ray S;Harrys Kishore CJ;Kanth S;Ahmed M;Kashyap MK;Mohmood R;Ramachandra YL;Krishna V;Rahiman BA;Mohan S;Ranganathan P;Ramabadran S;Chaerkady R;Pandey A
人类蛋白质参考数据库（HPRD-http：//www.hprd.org/）最初于2003年描述，是与人类蛋白质有关的精选蛋白质组学信息的数据库。我们最近在HPRD中添加了一些新功能。其中包括PhosphoMotif，它允许用户在感兴趣的蛋白质中找到超过320个实验验证的磷酸化基序。另一个新功能是蛋白质分布式注释系统-Human Proteinpedia（http：//www.humanProteinpedia.org/）-实验室可以通过该系统提交数据，并将其映射到HPRD中的蛋白质条目上。超过75个参与蛋白质组学研究的实验室已经参与了这项工作，提交了超过15000种人类蛋白质的数据。提交的数据包括质谱和蛋白质微阵列衍生数据以及其他数据类型。最后，HPRD还与我们的小组NetPath（http：//www.netpath.org/）开发的人类信号传导途径的纲要相关联，该纲要目前包含几种癌症和免疫信号传导途径的注释。自上次更新以来，已添加了5500多个新的蛋白质序列，使HPRD成为研究人类蛋白质组的综合资源。
Human Protein Reference Database (HPRD—http://www.hprd.org/), initially described in 2003, is a database of curated proteomic information pertaining to human proteins. We have recently added a number of new features in HPRD. These include PhosphoMotif Finder, which allows users to find the presence of over 320 experimentally verified phosphorylation motifs in proteins of interest. Another new feature is a protein distributed annotation system—Human Proteinpedia (http://www.humanproteinpedia.org/)—through which laboratories can submit their data, which is mapped onto protein entries in HPRD. Over 75 laboratories involved in proteomics research have already participated in this effort by submitting data for over 15 000 human proteins. The submitted data includes mass spectrometry and protein microarray-derived data, among other data types. Finally, HPRD is also linked to a compendium of human signaling pathways developed by our group, NetPath (http://www.netpath.org/), which currently contains annotations for several cancer and immune signaling pathways. Since the last update, more than 5500 new protein sequences have been added, making HPRD a comprehensive resource for studying the human proteome.
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影响因子：
3
作者：
Berger SI;Posner JM;Ma'ayan A
通讯作者：
Ma'ayan A
影响因子：
14.9
作者：
von Mering C;Jensen LJ;Kuhn M;Chaffron S;Doerks T;Krüger B;Snel B;Bork P
通讯作者：
Bork P
影响因子：
14.9
作者：
通讯作者：
--
Slimfinder：一种概率方法，用于识别蛋白质中占代表性过多的短线线性基序。
影响因子：
3.7
作者：
Edwards, Richard J.;Davey, Norman E.;Shields, Denis C.
通讯作者：
Shields, Denis C.
影响因子：
14.9
作者：
Peri, S;Navarro, JD;Pandey, A
通讯作者：
Pandey, A