Cross-sectional investigation of correlation between hepatic steatosis and IVIM perfusion on MR imaging.
Cross-sectional investigation of correlation between hepatic steatosis and IVIM perfusion on MR imaging.
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DOI：
10.1016/j.mri.2011.12.013
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发表时间：
2012-05
影响因子：
2.5
通讯作者：
Bydder, Mark
中科院分区：
文献类型：
--
作者：
Lee, James T.;Liau, Joy;Murphy, Paul;Schroeder, Michael E.;Sirlin, Claude B.;Bydder, Mark
本研究的目的是探讨肝脏脂肪分数（FF）和扩散参数之间的关系，来自体素内非相干运动（IVIM）模型。36例疑似非酒精性脂肪性肝病（NAFLD）的受试者接受了10个b值的弥散加权（DW）MR成像和6个回波的脂肪定量的扰相梯度回波成像。测量FF、R2 *、扩散率（D）和灌注分数（f）之间的相关性。主要发现是D与FF或f与FF之间没有显著相关性。D与R2 *（r =-0.490，p = 0.002）和f与D（r =-0.458，p = 0.005）具有显著相关性。结论是，肝脂肪变性不影响灌注或扩散的测量，因此不太可能混淆使用表观扩散率来评价肝纤维化。
The purpose of this study was to investigate the relationship between liver fat-fraction (FF) and diffusion parameters derived from the intravoxel incoherent motion (IVIM) model. 36 subjects with suspected nonalcoholic fatty liver disease (NAFLD) underwent diffusion weighted (DW) MR imaging with 10 b-values and spoiled gradient recalled echo imaging for fat quantification with six echos. Correlations were measured between FF, R2*, diffusivity (D) and perfusion fraction (f). The primary finding was that no significant correlation was obtained for D vs FF or f vs FF. Significant correlations were obtained for D vs R2* (r = −0.490, p = 0.002) and f vs D (r = −0.458, p = 0.005). The conclusion is that hepatic steatosis does not affect measurement of perfusion or diffusion and therefore is unlikely to confound the use of apparent diffusivity to evaluate hepatic fibrosis.
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影响因子：
4.4
作者：
Moteki, Takao;Horikoshi, Hiroyuki
通讯作者：
Horikoshi, Hiroyuki
影响因子：
19.7
作者：
Luciani, Alain;Vignaud, Alexandre;Rahmouni, Alain
通讯作者：
Rahmouni, Alain
影响因子：
4.4
作者：
Boss, Andreas;Martirosian, Petros;Schick, Fritz
通讯作者：
Schick, Fritz
影响因子：
6.2
作者：
Seifalian, AM;Piasecki, C;Davidson, BR
通讯作者：
Davidson, BR
DOI：
10.2214/ajr.09.2601
发表时间：
2009-07
期刊：
AJR. American journal of roentgenology
影响因子：
--
作者：
Taouli B;Ehman RL;Reeder SB
通讯作者：
Reeder SB