The presumed receptivity and susceptibility to monkeypox of European animal species.
The presumed receptivity and susceptibility to monkeypox of European animal species.
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DOI：
10.1016/j.idnow.2022.06.006
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发表时间：
2022-08
影响因子：
3.5
通讯作者：
Haddad, Nadia
中科院分区：
文献类型：
--
作者：
Haddad, Nadia
猴痘病毒属于正痘病毒属，就像人类特有的天花病毒一样。它是人畜共患的，以前从未被认为能够在9个以上的病毒产生周期内进行人际传播。虽然相关的动物宿主尚未确定，但非人类灵长类动物（NHP）只是偶然宿主。在临床阶段（最多3周），目前可能有大量人类脱壳，这在我们各国提出了动物被受感染人类污染的风险问题（反向人畜共患病）。猫和牛一样容易感染牛痘病毒，这是另一种人畜共患的正痘病毒，它们将这种病毒传播给人类。狗对这种病毒的易感性要低得多，似乎只接受牛痘病毒（也属于正痘病毒属）。另一方面，一项研究表明，成年白化兔和几种啮齿动物的幼鼠对猴痘病毒（MPXV）具有明显的易感性。考虑到草原犬鼠（美洲鼠科）对MPXV的易感性，不能排除欧洲松鼠感染的可能性。
The Monkeypox virus belongs to the Orthopoxvius genus, as does the specifically human smallpox virus. It is zoonotic and had never previously been considered as capable of human-to-human transmission over more than nine viral generation cycles. While relevant animal reservoirs have yet to be identified, non-human primates (NHP) are only accidental hosts. The potentially high number of current human shedders during the clinical phase (3 weeks maximum) raises the question of a risk in our countries of animals being contaminated by infected humans (reverse zoonosis). Cats as well as cows are susceptible to the Cowpox virus, another zoonotic Orthopoxvirus, which they transmit to humans. Dogs are much less susceptible to this virus and seem only receptive to Vaccinia virus (also belonging to the Orthopoxvirus genus). On the other hand, one study has demonstrated the pronounced susceptibility of the adult albino rabbit and of young animals of several rodent species to Monkeypox virus (MPXV). Given the susceptibility to MPXV of prairie dogs, which are American Sciuridae, the potential for infection of European squirrels cannot be ruled out.
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DOI：
10.1093/infdis/jiaa559
发表时间：
2022-04-19
期刊：
The Journal of infectious diseases
影响因子：
--
作者：
通讯作者：
--
影响因子：
11.8
作者：
Nguyen PY;Ajisegiri WS;Costantino V;Chughtai AA;MacIntyre CR
通讯作者：
MacIntyre CR
影响因子：
3.7
作者：
Nakazawa, Yoshinori;Lash, R. Ryan;Peterson, A. Townsend
通讯作者：
Peterson, A. Townsend
影响因子：
3.5
作者：
Tiee, Madeline S.;Harrigan, Ryan J.;Smith, Thomas B.
通讯作者：
Smith, Thomas B.
影响因子：
158.5
作者：
Reed, KD;Melski, JW;Damon, IK
通讯作者：
Damon, IK