Myocardial infarction caused by pharmacological substances - case description and literature review.

Myocardial infarction caused by pharmacological substances - case description and literature review.
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DOI:
10.5114/pwki.2013.37504
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发表时间:
2013
期刊:
Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
影响因子:
--
通讯作者:
Czarnecka D
Czarnecka D
中科院分区:
其他
文献类型:
--
作者:
Kameczura T;Bryniarski L;Surowiec S;Kocowska M;Kawecka-Jaszcz K;Czarnecka D

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心肌梗塞(MI)最常见是由冠状动脉壁的动脉粥样硬化和/或炎症过程引起的。这些现象的后果是动脉粥样硬化斑块的不稳定、凝血级联的激活以及阻塞血管腔的血栓形成。血管痉挛和微栓塞可能参与 MI 发病机制。对于诊断为心肌梗死的年轻人,冠状动脉造影通常无法显示任何病变。据报道,1%至12%的患者会发生冠状动脉无明显变化的心肌梗死。在这篇文章中,我们重点关注可能导致心肌梗死的化学物质,其中包括药物。
Myocardial infarction (MI) is most commonly caused by atherosclerosis and/or inflammatory processes of coronary artery walls. The consequence of those phenomena is instability of the atherosclerotic plaque, activation of the coagulation cascade and thrombus formation which occludes the lumen of the vessel. Vasospasm and microembolisation may participate in MI pathogenesis. In young individuals with diagnosis of MI, coronarography often reveals no pathologies. Is reported that MIs without significant changes of the coronary arteries occur in 1% to 12% of patients. In this article we focus on chemical substances, medicines among them, which can be a cause of MI.
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