A method to noninvasively identify cardiac bioelectrical sources.
A method to noninvasively identify cardiac bioelectrical sources.
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一种非侵袭性鉴定心脏生物电源的方法。
DOI：
10.1111/pace.12380
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发表时间：
2014-08
期刊：
影响因子：
--
通讯作者：
Armoundas AA
中科院分区：
文献类型：
--
作者：
Sohn K;Lv W;Lee K;Galea A;Hirschman G;Barrett C;Cohen RJ;Armoundas AA
我们引入了一种引导射频导管消融 (RCA) 程序的方法，该方法使用单等效移动偶极子 (SEMD) 估计用于起搏心室的导管尖端的位置以及消融的目标部位。研究该方法在解析心外膜和心内膜电源方面的准确性。两个电极阵列（每一个具有已知距离的九个起搏电极）缝合在猪的左心室和右心室（LV 和 RV）心外膜表面，用于以多种速率起搏心脏，同时记录 64 个部位的体表电位并用于估计 SEMD 位置。通过左心室和右心室导管起搏也采用了类似的方法。估计相邻心外膜电极的电极间距离的总体（RV 和 LV）误差为 0.38 ± 0.45 cm。总体心内膜（RV 和 LV）电极间距离误差为 0.44 ± 0.26 cm。心率对SEMD估计位置的误差没有显着影响（P > 0.05）。随着SEMD接近心外膜目标部位并接近目标，引导过程误差逐渐变小，总体绝对误差约为0.28 cm。估计的心外膜 SEMD 位置相对于心外膜电极的相应物理位置保留了其在图像空间中的拓扑。所提出的算法表明人们可以有效、准确地解析心外膜电源，而不需要成像方式。此外，解决这些来源的错误足以指导 RCA 程序。 （佩斯 2014 年；37：1038–1050）
We have introduced a method to guide radiofrequency catheter ablation (RCA) procedures that estimates the location of a catheter tip used to pace the ventricles and the target site for ablation using the single equivalent moving dipole (SEMD). To investigate the accuracy of this method in resolving epicardial and endocardial electrical sources. Two electrode arrays, each of nine pacing electrodes at known distances from each other, sutured on the left- and right-ventricular (LV and RV) epicardial surfaces of swine, were used to pace the heart at multiple rates, while body surface potentials from 64 sites were recorded and used to estimate the SEMD location. A similar approach was followed for pacing from catheters in the LV and RV. The overall (RV & LV) error in estimating the interelectrode distance of adjacent epicardial electrodes was 0.38 ± 0.45 cm. The overall endocardial (RV & LV) interelectrode distance error, was 0.44 ± 0.26 cm. Heart rate did not significantly affect the error of the estimated SEMD location (P > 0.05). The guiding process error became progressively smaller as the SEMD approached an epicardial target site and close to the target, the overall absolute error was ~0.28 cm. The estimated epicardial SEMD locations preserved their topology in image space with respect to their corresponding physical location of the epicardial electrodes. The proposed algorithm suggests one can efficiently and accurately resolve epicardial electrical sources without the need of an imaging modality. In addition, the error in resolving these sources is sufficient to guide RCA procedures. (PACE 2014; 37:1038–1050)
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影响因子：
3.8
作者：
Armoundas, AA;Feldman, AB;Cohen, RJ
通讯作者：
Cohen, RJ
影响因子：
10.8
作者：
ROSENBAUM, DS;WILBER, DJ;GARAN, H
通讯作者：
GARAN, H
影响因子：
3.7
作者：
Stevenson, W G;Delacretaz, E
通讯作者：
Delacretaz, E
影响因子：
37.8
作者：
SMITH, JM;CLANCY, EA;COHEN, RJ
通讯作者：
COHEN, RJ
影响因子：
82.9
作者：
Ramanathan, C;Ghanem, RN;Rudy, Y
通讯作者：
Rudy, Y