Cardiac autonomic activity during simulated shift work.
Cardiac autonomic activity during simulated shift work.
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DOI：
10.2486/indhealth.2018-0044
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发表时间：
2019-02-05
影响因子：
2
通讯作者：
VAN Dongen HPA
中科院分区：
文献类型：
--
作者：
Skornyakov E;Gaddameedhi S;Paech GM;Sparrow AR;Satterfield BC;Shattuck NL;Layton ME;Karatsoreos I;VAN Dongen HPA
倒班工作会导致不利的健康后果，包括增加心血管疾病的风险。心率(HR)和心率变异性(HRV)是心脏自主神经活动的量度，也是心血管疾病和死亡率的标志。为了研究轮班工作对心脏自主神经活动的影响，我们评估了模拟夜间工作对心率和心率变异性的影响，并将昼夜节律失调的直接影响与睡眠移位和体力活动模式改变的直接影响分开。共有29名受试者参加了两项实验室内模拟轮班工作研究中的一项。在这两项研究中，通过Holter监护仪连续监测EKG以测量HR和HRV的高频成分(HF-HRV)。我们发现HR和HF-HRV存在内源性昼夜节律性。在模拟夜间工作中，睡眠和清醒的体力活动都被替换了，对HR和HF-HRV有更实质性的相反的影响。我们的发现表明，一天中的时间、睡眠/清醒状态和体力活动对心脏自主神经活动的系统但复杂的交互影响。在评估轮班工作环境中的心率和心率变异性时，以及在将心脏自主神经活动的这些测量解释为心血管疾病的标志时，需要考虑这些影响。
Shift work leads to adverse health outcomes including increased risk of cardiovascular disease. Heart rate (HR) and heart rate variability (HRV) are measures of cardiac autonomic activity and markers of cardiovascular disease and mortality. To investigate the effects of shift work on cardiac autonomic activity, we assessed the influence of simulated night work on HR and HRV, and dissociated the direct effects of circadian misalignment from those of sleep displacement and altered physical activity patterns. A total of 29 subjects each participated in one of two in-laboratory, simulated shift work studies. In both studies, EKG was continuously monitored via Holter monitors to measure HR and the high frequency (HF) component of HRV (HF-HRV). We found endogenous circadian rhythmicity in HR and HF-HRV. Sleep and waking physical activity, both displaced during simulated night work, had more substantial, and opposite, effects on HR and HF-HRV. Our findings show systematic but complex, interacting effects of time of day, sleep/wake state, and physical activity on cardiac autonomic activity. These effects need to be taken into account when evaluating HR and HRV in shift work settings and when interpreting these measures of cardiac autonomic activity as markers of cardiovascular disease.
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影响因子：
4.8
作者：
Brum MC;Filho FF;Schnorr CC;Bottega GB;Rodrigues TC
通讯作者：
Rodrigues TC
影响因子：
2.8
作者：
Folkard, Simon
通讯作者：
Folkard, Simon
DOI：
10.1590/s0100-879x2002000800018
发表时间：
2002-08-01
影响因子：
2.3
作者：
Javorka, M.;Zila, I.;Javorka, K.
通讯作者：
Javorka, K.
影响因子：
37.8
作者：
Furlan, R;Barbic, F;Malliani, A
通讯作者：
Malliani, A
影响因子：
56.9
作者：
AKSELROD, S;GORDON, D;COHEN, RJ
通讯作者：
COHEN, RJ