Shift work and its association with metabolic disorders.
Shift work and its association with metabolic disorders.
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DOI：
10.1186/s13098-015-0041-4
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发表时间：
2015
影响因子：
4.8
通讯作者：
Rodrigues TC
中科院分区：
文献类型：
--
作者：
Brum MC;Filho FF;Schnorr CC;Bottega GB;Rodrigues TC
虽然倒班工作的健康负担还没有得到广泛的研究，但有证据表明，它可能会影响代谢平衡，并导致肥胖和其他代谢紊乱。睡眠不足、昼夜节律不同步以及饮食和体力活动中的行为变化是夜间工作与代谢紊乱之间的关系研究中最常提到的因素。个人对夜班工作的适应在很大程度上取决于家庭和社会生活等个人因素，但职业干预也可能对过渡到轮班工作做出积极贡献，例如在夜班期间暴露在明亮的灯光下，使用褪黑激素，轮班规律和顺时针轮换，以及适应夜间工作人员的代谢需求。对夜班工作对健康的影响以及这种关系背后的机制的评估可以作为干预战略的基础，以最大限度地减少轮班工作的健康负担。本综述旨在确定夜间和轮班工作与代谢紊乱之间的关系以及导致这些关系的机制和途径之后的治疗意义。
Although the health burden of shift work has not been extensively studied, evidence suggests that it may affect the metabolic balance and cause obesity and other metabolic disorders. Sleep deprivation, circadian desynchronization and behavioral changes in diet and physical activity are among the most commonly mentioned factors in studies of the association between night work and metabolic disorders. Individual adaptation to night work depends greatly on personal factors such as family and social life, but occupational interventions may also make a positive contribution to the transition to shift work, such as exposure to bright lights during the night shift, melatonin use, shift regularity and clockwise rotation, and dietary adaptations for the metabolic needs of night workers. The evaluation of the impact of night work on health and of the mechanisms underlying this relationship can serve as a basis for intervention strategies to minimize the health burden of shift work. This review aimed to identify highlights regarding therapeutic implications following the association between night and shift work and metabolic disorders, as well as the mechanisms and pathways responsible for these relationships.
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影响因子：
16.2
作者：
Cappuccio FP;D'Elia L;Strazzullo P;Miller MA
通讯作者：
Miller MA
影响因子：
3
作者：
de Gaudemaris, Regis;Levant, Aude;Lang, Thierry
通讯作者：
Lang, Thierry
影响因子：
4.4
作者：
Kawabe, Yuri;Nakamura, Yasuyuki;Ueshima, Hirotsugu
通讯作者：
Ueshima, Hirotsugu
影响因子：
7.7
作者：
De Bacquer, D.;Van Risseghem, M.;Braeckman, L.
通讯作者：
Braeckman, L.
影响因子：
4.2
作者：
Hannerz, H;Albertsen, K;Burr, H
通讯作者：
Burr, H