Smokers' Neurological Responses to Novel and Repeated Health Warning Labels (HWLs) From Cigarette Packages.

Smokers' Neurological Responses to Novel and Repeated Health Warning Labels (HWLs) From Cigarette Packages.
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DOI:
10.3389/fpsyt.2018.00319
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发表时间:
2018
影响因子:
4.7
通讯作者:
Thrasher JF
Thrasher JF
中科院分区:
医学3区
文献类型:
--
作者:
Fridriksson JF;Rorden C;Newman-Norlund RD;Froeliger B;Thrasher JF

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描述因吸烟而造成的身体伤害的图形健康警告标签(HWL)对于改变成年吸烟者的情感、认知和吸烟行为是有效的。然而,对重复呈现图形HWL对上述过程的影响知之甚少。本研究的目的是检测对图形HWL的神经和行为反应,并评估重复呈现图形HWL是否会导致重复抑制(RS)。吸烟者(N=16)执行与事件相关的HWL提示任务,同时在功能磁共振成像(FMRI)实验期间收集血氧水平依赖(BOLD)信号。与之前的文献一致,与混乱的图像相比,图形HWL在涉及自我参照和情绪处理的大脑区域引发了更多的大胆反应。重要的是,在重复呈现相同的HWL期间,该网络中的站点的大胆反应减少了。这些发现表明,虽然新颖的图形HWL可能对吸烟者的大脑活动有显著影响,但重复呈现可能会导致反应减弱,从而限制他们诱导行为变化的潜力。
Graphic health warning labels (HWLs) depicting bodily injury due to smoking are effective for producing changes in affect, cognition and smoking behavior in adult smokers. However, little is known about the effects of repeated presentation of graphic HWL's on the aforementioned processes. The goal of this study was to examine neural and behavioral responses to graphic HWL's and evaluate whether the repeated presentation of graphic HWL's leads to repetition suppression (RS). Smokers (N = 16) performed an event-related HWL cue task while blood oxygen level dependent (BOLD) signal was collected during a functional magnetic resonance imaging (fMRI) experimental session. Consistent with prior literature, graphic HWL's, as compared to scrambled images, elicited increased BOLD response in brain regions involved in self-referential and emotion processing. Importantly, BOLD response at sites in this network diminished during repeated presentation of the same HWL. These findings suggest that while novel graphic HWL's may have a significant effect on smokers' brain activity, repeated presentation may lead to muted responses and thus limit their potential to induce behavioral change.
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